Results 211 to 220 of about 320,850 (300)

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

open access: yesBMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen   +9 more
wiley   +1 more source

LPCAT3 is essential for leukemia progression and represents a therapeutic vulnerability in AML. [PDF]

open access: yesBlood Sci
Cao M   +8 more
europepmc   +1 more source

Phagocyte Chemotaxis

open access: yesJournal of Investigative Dermatology, 1979
openaire   +2 more sources

Secretopathies emerge as a new class of neurocristopathies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira   +3 more
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Towards light-coupled sample preparation for time-resolved cryoEM studies. [PDF]

open access: yesIUCrJ
Hadjidemetriou K   +9 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou   +6 more
wiley   +1 more source

Age, embryo donor status, and insemination with chilled semen all predispose to persistent breeding‐induced endometritis in warmblood mares

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Persistent breeding‐induced endometritis (PBIE) is a common reason for mares failing to establish pregnancy. Objective To examine the hypothesis that advancing mare age and embryo donor status predispose to PBIE and compromise fertility.
Tom Stout   +3 more
wiley   +1 more source

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