Results 231 to 240 of about 320,850 (300)

Impact of abrasive versus non‐abrasive cleaning on peri‐implantitis titanium release: A randomized clinical trial

Journal of Periodontology, EarlyView.
Abstract Background Surface decontamination is integral to peri‐implantitis treatment. However, abrasive mechanical methods can cause implant surface degradation with possible adverse biological effects. No human studies have examined whether these treatments cause titanium release or impair regenerative outcomes.
Georgios A. Kotsakis, Antonella Botto, Marzieh S. Jazaeri, Archontia Palaiologou, Eddie Lee, Diane M. Daubert   +5 more
wiley   +1 more source

Managing the meniscus Part 2: Traumatic tear patterns, biologic augmentation, transplantation, innovation and future research

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Acute, traumatic meniscus tears are common and should be repaired whenever possible. However, the biological age of the patient, along with the specific tear morphology, may significantly influence the selection of the repair technique, expected clinical outcomes and the postoperative rehabilitation protocol.
Armin Runer, Matthew P. Kolevar, Ehab M. Nazzal, Jonathan D. Hughes, Sebastian Kopf, Aaron J. Krych, Michael T. Hirschmann, Robert F. LaPrade, Alan Getgood, Tim Spalding, Robert Prill, Maria Tuca, Matthieu Ollivier, Sebastian Siebenlist, Sachin Tapasvi, Volker Musahl   +15 more
wiley   +1 more source

Myeloid Focal Adhesion Kinase Promotes Macrophage Accumulation but Does Not Alter Tumor Progression in Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Hepatocellular carcinoma (HCC) develops within an immunologically complex tumor microenvironment that is heavily shaped by infiltrating myeloid cells. Immune‐based treatment strategies such as atezolizumab plus bevacizumab have shown promising therapeutic benefits, but patients do not experience durable responses.
Eugene Ham, Kyle Boedeker, Claudia Rose Keating, Ruisong Ye, Frankie Montalbano, Sophia Mankaruse, Xianzhong Ding, Jonathan P. Rennhack, Wei Qiu   +8 more
wiley   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

Med Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang, Fen Yang, Xingji Lian, Jie He, Shuijin Huang, Mingjuan Fan, Yin Liang, Jiaqiang Huang, LongYan Yin, Hong Wang   +9 more
wiley   +1 more source

Recent Advances in Exosome‐Based Nanodelivery Systems for Traumatic Brain Injury Treatment

Med Research, EarlyView.
An overview of functional modification, therapeutic effects, molecular composition, and delivery strategies for exosomes. ABSTRACT Traumatic brain injury (TBI) is a highly heterogeneous neurological condition with extremely high rates of mortality and disability.
Jue Zhu, Weiquan Liao, Ziqi Lian, Mengdan Zhang, Chenxing Wang, Xingjia Zhu, Lin Zhang, Jian Chen, Zhichao Lu, Peipei Gong   +9 more
wiley   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Protocol to explore olfactory placode morphogenesis using an agent-based model. [PDF]

STAR Protoc
Demont V, Letort G, Sanchez D, Batut J.
europepmc   +1 more source

Adoptive transfer of VSIG4⁺ macrophages interrupts the CCL2-CCR2 inflammatory amplification loop to mitigate acetaminophen-induced acute liver injury in murine and human organoid models. [PDF]

J Transl Med
Duan B, Chen J, Liu G, Lin J, Yang S, Kong X, Rong W, Tan W.   +7 more
europepmc   +1 more source

SMYD2 regulates lymph node metastasis derived from intrahepatic cholangiocellular carcinoma through CCR7-dependent chemotaxis. [PDF]

Sci Rep
Nakamura M, Hayami S, Miyamoto A, Suzaki N, Yoshimura T, Nakamura K, Shigekawa Y, Shimizu A, Kitahata Y, Takeuchi A, Motobayashi H, Matsumoto K, Ehata S, Hamamoto R, Kawai M.   +14 more
europepmc   +1 more source

Cervical lymph node response to 131I therapy in differentiated thyroid cancer using radiomics and clinical features. [PDF]

Front Oncol
Ruan Y, Yuan H, Zheng F, Chen X, Xu C.
europepmc   +1 more source