Results 81 to 90 of about 328,071 (298)

Sperm Chemotaxis - A primer

, 2005
Sperm become attracted by chemical substances that are released from the outer coating of the egg, a process called chemotaxis. In this paper the cellular pathway and the motor response during chemotaxis of sperm from sea urchin and starfish are briefly ...
E. HILDEBRAND, U. B. KAUPP, Hildebrand, E., Kaupp, U. B.   +3 more
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

COP5/HKR1 changes ciliary beat pattern and biases cell steering during chemotaxis in Chlamydomonas reinhardtii

Scientific Reports
This study investigates the control of ciliary beat patterns during ammonium chemotaxis in the model ciliate microalga Chlamydomonas reinhardtii. Screening the chemotaxis response of mutant strains with ciliary defects revealed that a strain lacking CAV2,
Alexis Strain, Nathan Kratzberg, Dan Vu, Emmaline Miller, Ken-ichi Wakabayashi, Adam Melvin, Naohiro Kato   +6 more
doaj   +1 more source

Psoriasis and Leukocyte Chemotaxis.

Journal of Investigative Dermatology, 1987
Transepidermal migration of leukocytes, with resultant formation of microscopic or macroscopic sterile subcorneal pustules is a phenomenon characteristically noted in psoriasis and related sterile pustular dermatoses. It is natural to assume the presence of potent neutrophil chemotactic substances in the subcorneal portion of the lesional epidermis ...
Tagami, Hachiro, Iwatsuki, Keiji, Takematsu, Hideaki   +2 more
openaire   +2 more sources

An evaluation of the Agrobacterium tumefaciens Virulence gene system as a potential diagnostic test for Neuroblastoma. [PDF]

, 1993
Neuroblastoma is a common pediatric cancer, the prognosis for which is markedly dependent upon the progression of the disease at the time of diagnosis.
Palmer, Adrian Charles Vernon
core  

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Quantitative chemical biosensing by bacterial chemotaxis in microfluidic chips: Chemotaxis-microfluidic biosensor [PDF]

, 2017
Whole-cell bacterial bioreporters are proposed as alternatives to chemical analysis of, for example, pollutants in environmental compartments. Commonly based on reporter gene induction, bioreporters produce a detectable signal within 30 min to a few ...
Mazza, Christian (author), Van Der Meer, Jan Roelof, Roggo, Clémence (author), Meer, Jan Roelof van der, Richard, Xavier (author), Roggo, Clémence, Mazza, Christian, Lintel, Harald van, van der Meer, Jan Roelof (author), Picioreanu, Cristian, Picioreanu, C., Harald van Lintel, Christian Mazza, Jan Roelof van der Meer, Picioreanu, C. (author), Richard, Xavier, Clémence Roggo, Cristian Picioreanu, Van Lintel, Harald, Xavier Richard, van Lintel, Harald (author), Richard, X., van der Meer, J.R., Mazza, C., Richard X, van Lintel, H., Mazza C, van der Meer JR, Roggo C, Roggo, C., van Lintel H, Picioreanu C   +31 more
core   +2 more sources

Single‐Dose TACE‐Like Injection of Sustained‐Release Panobinostat/IL‐12 Polymeric Microparticles is Effective in Preclinical Liver Cancer Models

Advanced Science, EarlyView.
A novel PLGA/PBAE polymer microparticle platform revolutionizes intermediate‐stage liver cancer treatment by co‐delivering panobinostat and IL‐12 via a single TACE‐like injection. This sustained‐release system overcomes tumor immunosuppression, triggers robust innate and adaptive immune responses, and establishes tertiary lymphoid structures ...
Hongzhe Yu, Ling Li, Sachin S. Surwase, Xin Ming M. Zhou, Hongtao Qian, Joel C. Sunshine, Florin M. Selaru, Jordan J. Green   +7 more
wiley   +1 more source

A high-throughput chemotaxis assay for assessing immunotoxicity using multiple human immune cell types

NAM Journal
New approach methodologies (NAMs) for immunotoxicity are critically needed for rapidly identifying immunotoxicants, filling gaps for data-poor chemicals, and reducing the number of vertebrate animals used in toxicity testing.
Drake W. Phelps, Nadia Barbo, Stephanie N. Caty, Joshua A. Harrill, Kimberly Slentz-Kesler   +4 more
doaj   +1 more source

A real time chemotaxis assay unveils unique migratory profiles amongst different primary murine macrophages.

PLoS ONE, 2013
Chemotaxis assays are an invaluable tool for studying the biological activity of inflammatory mediators such as CC chemokines, which have been implicated in a wide range of chronic inflammatory diseases.
Asif J Iqbal, Daniel Regan-Komito, Ivy Christou, Gemma E White, Eileen McNeill, Amy Kenyon, Lewis Taylor, Theodore S Kapellos, Edward A Fisher, Keith M Channon, David R Greaves   +10 more
doaj   +1 more source