Results 171 to 180 of about 245,930 (217)

Neutrophils alter the metabolic profile of a coculture model of triple-negative breast cancer and stromal cells. [PDF]

BMC Cancer
Salzer AT, Williams C, Skoluda S, Stylianou M, Gilthorpe JD, Urban CF.   +5 more
europepmc   +1 more source

Molecular Active Matter, Kinetic Asymmetry, and Non‐Reciprocal Interactions

Small, EarlyView.
Nanoscale enzymes constitute dissipative active matter that converts scalar energy input into vectorial outputs. Through kinetic and diffusion asymmetry, they break time and space symmetry, resulting in directional motion. This mechanism accounts for both positive and negative chemotaxis, as well as non‐reciprocal interactions between enzymes that ...
Niladri Sekhar Mandal, Xiaotian Lu, Ayusman Sen, R. Dean Astumian   +3 more
wiley   +1 more source

Divergent chemotactic sensing in <i>Acanthamoeba</i> reveals ligand-promiscuous, threshold-tuned pattern recognition without canonical formyl peptide receptors. [PDF]

Microlife
Hermaraj V, Wren BW, Nasher F.
europepmc   +1 more source

Negative Chemotaxis of Urease‐Functionalized Polymeric Microcapsules

Small, EarlyView.
Urease‐functionalized PLGA microcapsules exhibit negative chemotaxis in urea gradients, migrating from high to low substrate concentrations. Increasing gradients enhance chemotaxis until a plateau, while increasing average substrate concentration in a fixed gradient reverses chemotactic behavior.
Amanda Hopkins, Daeyeon Lee, Daniel A. Hammer   +2 more
wiley   +1 more source

3D chemotaxis chip for investigating natural killer cell migration mechanisms. [PDF]

Front Immunol
Temples MN, Lightsey S, Conklin T, Newport RS, Phelps EA, Sharma B.   +5 more
europepmc   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng, Hui‐Jun Qiu, Ming‐Rui Pan, Qin‐Tai Yang   +3 more
wiley   +1 more source

Decoding neuro-tumor interactions in pancreatic cancer: mechanisms, immunosuppressive networks and therapeutic opportunities. [PDF]

Mol Biomed
Cheng W, Cao H, Hu H, Qian R, Xu B, Zhang J.   +5 more
europepmc   +1 more source

Current Advances of Treatments, Therapeutic Targets, Biomarkers, Novel Drugs, and Machine Learning for Hypopharyngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li, Rui Guan, Rui‐Jie Jiao, Zhi‐Jie Bi, Yang Fu, Yin Wang, Chen‐Yang Xu, Ye Qian, Ran Wei, Sheng‐Da Cao, Wen‐Ming Li, Dong‐Min Wei, Da‐Peng Lei   +12 more
wiley   +1 more source