Results 81 to 90 of about 212,420 (268)

Adjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0–1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER database

BMC Cancer, 2020
Background The benefit of adjuvant chemotherapy in invasive lobular carcinoma (ILC) is still unclear. The objective of the current study was to elucidate the effectiveness of adjuvant chemotherapy in hormone receptor (HR)-positive, human epidermal growth
Guangfu Hu, Guangxia Hu, Chengjiao Zhang, Xiaoyan Lin, Ming Shan, Yanmin Yu, Yongwei Lu, Ruijie Niu, Hui Ye, Cheng Wang, Cheng Xu   +10 more
doaj   +1 more source

Bayesian Nonparametric Cost-Effectiveness Analyses: Causal Estimation and Adaptive Subgroup Discovery [PDF]

arXiv, 2020
Cost-effectiveness analyses (CEAs) are at the center of health economic decision making. While these analyses help policy analysts and economists determine coverage, inform policy, and guide resource allocation, they are statistically challenging for several reasons. Cost and effectiveness are correlated and follow complex joint distributions which are
arxiv  

Assessment of concurrent neoplasms and a paraneoplastic association in MOGAD

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Cases of myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) co‐occurring with neoplasms have been reported. In this international, retrospective cohort study in South Korea and the USA, 16 of 445 (3.6%) patients with MOGAD had concurrent neoplasm within 2 years of MOGAD onset, resulting in a standardized incidence ...
Young Nam Kwon, Nanthaya Tisavipat, Yong Guo, Stephanie B. Syc‐Mazurek, Ji Yeon Han, Jun‐Soon Kim, Kyomin Choi, Seong‐il Oh, Seok‐Jin Choi, Eunhee Sohn, Jeeyoung Oh, Seung Woo Kim, Ha Young Shin, Byung Chan Lim, Byoung Joon Kim, Kyung Seok Park, Jung‐Joon Sung, Se Hoon Kim, Sung‐Hye Park, Anastasia Zekeridou, Claudia F. Lucchinetti, Sean J. Pittock, John J. Chen, Eoin P. Flanagan, Sung‐Min Kim   +24 more
wiley   +1 more source

Localized stomach cancer: Perioperative or postoperative approach? A meta‐analysis of phase III studies

JGH Open, 2022
Background and Aim Despite the development and standardization of surgical techniques in the treatment of localized gastric adenocarcinoma, the loco‐regional and metastatic recurrence rate remains high.
Wala Ben Kridis, Haitham Rejab, Rafik Mzali, Jamel Daoud, Afef Khanfir   +4 more
doaj   +1 more source

A Novel 3D High‐Throughput Phenotypic Drug Screening Pipeline to Identify Drugs with Repurposing Potential for the Treatment of Ovarian Cancer

Advanced Healthcare Materials, EarlyView.
Ovarian cancer's high recurrence and therapy resistance demand new strategies. A high‐throughput drug screening pipeline using 3D spheroids, which showed poor concordance with 2D models, identified rapamycin as a promising candidate. In combination with cisplatin, rapamycin demonstrated significant in vitro and in vivo efficacy, highlighting the ...
Nazanin Karimnia, Amy L. Wilson, Brittany R. Doran, Jennie Do, Amelia Matthews, Gwo Y. Ho, Magdalena Plebanski, Thomas W. Jobling, Andrew N. Stephens, Maree Bilandzic   +9 more
wiley   +1 more source

PB2114: TREATMENT RESULTS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA FROM HIGH-RISK GROUP

HemaSphere, 2022
K. Filonenko, I. Kriachok, A. Martynchyk, I. Titorenko, Y. Stepanishyna, O. Aleksyk, K. Ukianchenko, I. Pastushenko, Y. Kushchevyy, O. Novosad, O. Karnabeda, I. Diagil, V. Kozlov   +12 more
doaj   +1 more source

Are Thousands of Samples Really Needed to Generate Robust Gene-List for Prediction of Cancer Outcome? [PDF]

arXiv, 2016
The prediction of cancer prognosis and metastatic potential immediately after the initial diagnoses is a major challenge in current clinical research. The relevance of such a signature is clear, as it will free many patients from the agony and toxic side-effects associated with the adjuvant chemotherapy automatically and sometimes carelessly subscribed
arxiv  

Injectable 2D‐MoS2‐integrated Bioadhesive Hydrogel as Photothermal‐Derived and Drug‐Delivery Implant for Colorectal Cancer Therapy

Advanced Healthcare Materials, EarlyView.
An injectable, adhesive hydrogel integrating 2D‐MoS2 and 5‐fluorouracil (AlgNB/MoS2/5‐FU) is developed for near‐infrared‐triggered photothermal therapy and localized drug delivery. The adhesive hydrogel demonstrates superior tumor anchoring, efficient photothermal conversion, and synergistic inhibition of colorectal cancer progression, offering a ...
Xiaojun Long, Jiawei Wang, Huijuan Wang, Kepeng Hu, Wei Zhang, Weiming Lin, Chao Fang, Kui Cheng, Zhangfa Song   +8 more
wiley   +1 more source

Multicentre study of perioperative versus adjuvant chemotherapy for resectable colorectal liver metastases

BJS Open, 2019
Background It is not known whether perioperative chemotherapy, compared with adjuvant chemotherapy alone, improves disease‐free survival (DFS) in patients with upfront resectable colorectal liver metastases (CLM).
M.‐A. Allard, Y. Nishioka, N. Beghdadi, K. Imai, M. Gelli, S. Yamashita, Y. Kitano, T. Kokudo, Y.‐I. Yamashita, A. Sa Cunha, E. Vibert, D. Elias, D. Cherqui, D. Goere, R. Adam, H. Baba, K. Hasegawa   +16 more
doaj   +1 more source

Body weight loss after surgery affects the continuity of adjuvant chemotherapy for pancreatic cancer

BMC Cancer, 2019
Background Postoperative chemotherapy is beneficial for many pancreatic cancer patients. However, some patients require dose reduction or the discontinuation of adjuvant chemotherapy because of adverse treatment-related effects.
Yoshifumi Morita, Takanori Sakaguchi, Ryo Kitajima, Satoru Furuhashi, Ryota Kiuchi, Makoto Takeda, Takanori Hiraide, Yasushi Shibasaki, Hirotoshi Kikuchi, Hiroyuki Konno, Hiroya Takeuchi   +10 more
doaj   +1 more source