Results 71 to 80 of about 280,575 (305)

Defining a positive circumferential resection margin in oesophageal cancer and its implications for adjuvant treatment [PDF]

, 2013
A positive circumferential resection margin (CRM) has been associated with a poorer prognosis in oesophageal and oesophagogastric junctional (OGJ) cancer. The College of American Pathologists defines the CRM as positive if tumour cells are present at the
Driscoll, P J, Paterson-Brown, S., Kamel, H. M., Phillips, H A, O'Neill, Robert, Stephens, Nathan A, Save, V   +6 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Early recurrence of pancreatic cancer after resection and during adjuvant chemotherapy

The Saudi Journal of Gastroenterology, 2012
Background/Aim: Adjuvant chemotherapy for 6 months is the current standard of care after potentially curative resection of pancreatic cancer and yields an overall survival of 15-20 months. Early tumor recurrence before or during adjuvant chemotherapy has
Richard Fischer, Matthias Breidert, Tobias Keck, Frank Makowiec, Christian Lohrmann, Jan Harder   +5 more
doaj   +1 more source

An integrated model of the transcriptome of HER2-positive breast cancer [PDF]

, 2013
Our goal in these analyses was to use genomic features from a test set of primary breast tumors to build an integrated transcriptome landscape model that makes relevant hypothetical predictions about the biological and/or clinical behavior of HER2 ...
Melissa Lau, High-seng Chai, David Rossell, Brian M. Necela (224867), Jeanette E. Eckel-Passow (228909), S. Keith Anderson (271824), Tang, Xiaojia, Rossell, David, Kevin J. Thompson (479037), E. Aubrey Thompson (224877), Sarah A McLaughlin, Baker, Tiffany R., Kalari, Krishna R., Necela, Brian M., Xiaojia Tang, Melissa Lau (479038), David Rossell (479046), Lau, Melissa, Derek C Radisky, Krishna R. Kalari (228899), Richard W. Joseph (479042), Sarah A. McLaughlin (479043), Camille, Stephan, Thompson, E. Aubrey, McLaughlin, Sarah A., S Keith Anderson, Saurabh Baheti, Tiffany R Baker, Jennifer M Kachergus, Jennifer M Carr, Joseph, Richard W., Asmann, Yan W., Kachergus, Jennifer M., Yan W. Asmann (210163), Zhifu Sun (60356), Derek C. Radisky (119628), Carr, Jennifer M., Richard W Joseph, Krishna R Kalari, Jennifer M. Carr (224872), Thompson, Kevin J., High-seng Chai (479044), Stephan Camille (479045), Kevin J Thompson, Poulami Barman (479041), Poulami Barman, Edith A Perez, Xiaojia Tang (53518), Saurabh Baheti (479040), Anderson, S. Keith, Barman, Poulami, Brian M Necela, Stephan Camille, Radisky, Derek C., Jennifer M. Kachergus (479039), Eckel-Passow, Jeanette E., Chai, High-seng, Perez, Edith A., Sun, Zhifu, E Aubrey Thompson, Yan W Asmann, Tiffany R. Baker (228915), Zhifu Sun, Baheti, Saurabh, Edith A. Perez (228921), Jeanette E Eckel-Passow   +65 more
core   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

HER2 and ESR1 mRNA expression levels and response to neoadjuvant trastuzumab plus chemotherapy in patients with primary breast cancer

, 2013
Introduction: Recent data suggest that benefit from trastuzumab and chemotherapy might be related to expression of HER2 and estrogen receptor (ESR1). Therefore, we investigated HER2 and ESR1 mRNA levels in core biopsies of HER2-positive breast carcinomas
Jens Huober, Reinisch, Mattea, Sibylle Loibl, Silvia Darb-Esfahani, Michael Untch, Hans Tesch, Martin-Leo Hansmann, Jan C Brase, Knut Engels, Judith Prinzler, Keyur Mehta, Minckwitz, Gunter von, Brase, Jan C., Kronenwett, Ralf, Hansmann, Martin-Leo, Huober, Jens, Engels, Knut, Solbach, Christine, Tesch, Hans, Carsten Denkert, Denkert, Carsten, Gunter von Minckwitz, Bruno V Sinn, Loibl, Sibylle, Mattea Reinisch, Peter A Fasching, Sinn, Bruno V., Ralf Kronenwett, Christine Solbach, Prinzler, Judith, Mehta, Keyur, Fasching, Peter Andreas, Untch, Michael, Denkert, Carsten Michael, Darb-Esfahani, Silvia   +34 more
core   +1 more source

Cisplatin-based chemotherapy of testicular cancer - Two decades after a major breakthrough [PDF]

, 2000
Two decades ago the introduction of cisplatin-based combination chemotherapy has dramatically improved the prognosis of patients with metastatic testicular cancer, At present 3 cycles of cisplatin, etoposide and bleomycin are considered as standard ...
Gerl, Arthur
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

PB2114: TREATMENT RESULTS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA FROM HIGH-RISK GROUP

HemaSphere, 2022
K. Filonenko, I. Kriachok, A. Martynchyk, I. Titorenko, Y. Stepanishyna, O. Aleksyk, K. Ukianchenko, I. Pastushenko, Y. Kushchevyy, O. Novosad, O. Karnabeda, I. Diagil, V. Kozlov   +12 more
doaj   +1 more source

Multivariate analysis of febrile neutropenia occurrence in patients with non-Hodgkin lymphoma: data from the INC-EU Prospective Observational European Neutropenia Study

, 2008
Summary Myelosuppression, particularly febrile neutropenia (FN), are serious dose-limiting toxicities that occur frequently during the first cycle of chemotherapy.
Impact of Neutropenia in Chemotherapy-European Study Group (INC-, Paridaens, R, Szucs, Thomas D., Matthias Schwenkglenks, Pettengell, R, Bosly, André, Schwenkglenks, Matthias, Jackisch, C, Jackisch, Christian, Thomas D. Szucs, Manuel Constenla, Constenla, Manuel, Szucs, T D, Schwenkglenks, M, André Bosly, Leonard, Robert, Paridaens, Robert, Christian Jackisch, Robert Leonard, Pettengell, Ruth, Ruth Pettengell, Robert Paridaens, Bosly, A, Impact of Neutropenia in Chemotherapy-European Study Group,, Szucs, TD, Leonard, R, Constenla, M   +26 more
core   +1 more source