Results 51 to 60 of about 800,324 (296)

Prognostic nutritional index is an independent risk factor for continuing S-1 adjuvant chemotherapy in patients with pancreatic cancer who received neoadjuvant chemotherapy and surgical resection

BMC Cancer
Purpose Reports on the association of perioperative nutritional and inflammatory status with the clinical course of adjuvant chemotherapy did not include neoadjuvant chemotherapy.
Shinnosuke Kawahara, Toru Aoyama, Masaaki Murakawa, Rei Kanemoto, Daishi Takahashi, Yuto Kamioka, Itaru Hashimoto, Yukio Maezawa, Satoshi Kobayashi, Makoto Ueno, Naoto Yamamoto, Takashi Oshima, Norio Yukawa, Yasushi Rino, Aya Saito, Soichiro Morinaga   +15 more
doaj   +1 more source

Adjuvant chemotherapy in node‐positive patients after esophagectomy for esophageal squamous cell carcinoma

Thoracic Cancer, 2023
Background The role of adjuvant chemotherapy in esophageal squamous cell carcinoma (ESCC) remains controversial. This study aimed to evaluate the impact of adjuvant chemotherapy on survival in patients with positive nodes after surgery for ESCC.
Yeong Jeong Jeon, Jong Ho Cho, Yong Soo Choi, Young Mog Shim, Jong‐Mu Sun, Hong Kwan Kim   +5 more
doaj   +1 more source

The benefits and harms of adjuvant chemotherapy for non-small cell lung cancer in patients with major comorbidities: A simulation study.

PLoS ONE, 2022
BackgroundRandomized controlled trials (RCTs) have demonstrated a survival benefit for adjuvant platinum-based chemotherapy after resection of locoregional non-small cell lung cancer (NSCLC).
Amanda Leiter, Chung Yin Kong, Michael K Gould, Minal S Kale, Rajwanth R Veluswamy, Cardinale B Smith, Grace Mhango, Brian Z Huang, Juan P Wisnivesky, Keith Sigel   +9 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Adjuvant Chemotherapy in Patients with Node-Negative Non-Small Cell Lung Cancer with Satellite Pulmonary Nodules in the Same Lobe

Journal of Chest Surgery, 2022
Background: According to the eighth TNM (tumor-node-metastasis) staging system, the presence of separate tumor nodules in the same lobe is designated as a T3 descriptor.
Jiyoun Park, Junghee Lee, Yeong Jeong Jeon, Sumin Shin, Jong Ho Cho, Hong-Kwan Kim, Yong Soo Choi, Jhingook Kim, Jae Ill Zo, Young Mog Shim   +9 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Benefit of adjuvant chemotherapy for resectable gastric cancer: A meta-analysis

, 2010
Context Despite potentially curative resection of stomach cancer, 50% to 90% of patients die of disease relapse. Numerous randomized clinical trials (RCTs) have compared surgery alone with adjuvant chemotherapy, but definitive evidence is lacking ...
BURZYKOWSKI T, OBA K, PAOLETTI X, NITTI, DONATO, SAKAMOTO J, PIGNON JP, VAN CUTSEM E, ROUGIER P, SARGENT D, GLOBAL ADVANCED ADJUVANT STOMACH TUMOR RESEARCH INTERNATIONAL COLLABORATION GROUP, MICHIELS S, SASAKO M, OHASHI Y   +12 more
core   +1 more source

Adverse events with S-1 adjuvant chemotherapy.

, 2020
Adverse events with S-1 adjuvant chemotherapy.
Masashi Nagata (3439952), Masafumi Nakamoto (3617828), Akimitsu Hiraki (3439943), Junki Sakata (3439940), Hideki Nakayama (2601604), Hikaru Nakashima (3439934), Ken Kikuchi (263550), Yuichiro Matsuoka (3439946), Ryoji Yoshida (3439949), Hidetaka Arita (3439928), Akiyuki Hirosue (3439931), Nozomu Takahashi (225748), Masatoshi Hirayama (503574), Masanori Shinohara (3617840), Kenta Kawahara (3439937)   +14 more
core   +1 more source

Optimizing the Choice for Adjuvant Chemotherapy in Gastric Cancer [PDF]

, 2022
Advances in the management of gastric cancer have improved patient survival in the last decade. Nonetheless, the number of patients relapsing and dying after a diagnosis of localized gastric cancer is still too high, even in early stages (10% in stage I).
Serena Veschi, Davide Brocco, Di Lisa, Francesca Sofia, Lorena Filomeno, Grassadonia, Antonino, Carletti, Erminia, Francesca Sofia Di Lisa, Laura De Lellis, Saverio Alberti, Brocco, Davide, Cama, Alessandro, Erminia Carletti, Patrizia Vici, Veschi, Serena, Rosalba Florio, De Lellis, Laura, Florio, Rosalba, Filomeno, Lorena, Antonella De Luca, Giuseppe Cicero, Vici, Patrizia, Cicero, Giuseppe, De Luca, Antonella, Alessandro Cama, Tinari, Nicola, Antonino Grassadonia, Nicola Tinari, Alberti, Saverio   +27 more
core   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source