Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao+4 more
wiley +1 more source
The adverse effects of chemotherapy on bone mass are not prevented by senolytics. [PDF]
Ali MM+7 more
europepmc +1 more source
Intra-Vitam Staining of Tuberculous Guinea-Pigs with Fat-Soluble Dyes (Supplementary Note): Studies on the Biochemistry and Chemotherapy of Tuberculosis. VI. [PDF]
H. J. Corper
openalex +1 more source
An Analysis for IDH‐Mutant Grade 4 Astrocytoma Based on WHO CNS 5: Implication of Clinical Practice
ABSTRACT Purpose There is ongoing debate regarding the therapeutic approach and prognosis for IDH‐mutant grade 4 astrocytoma, a newly defined subtype of diffuse glioma in the 2021 WHO classification system for central nervous system tumors (WHO CNS 5). The aim of this study was to explore the clinical outcome and prognosticators for newly diagnosed IDH‐
Xianxin Qiu+13 more
wiley +1 more source
Case Report: Fatal <i>Pneumocystis jirovecii</i> Infection in an Elderly Man Receiving Adjuvant Paclitaxel and Trastuzumab Therapy for HER2-Positive Breast Cancer. [PDF]
Vercueil C+3 more
europepmc +1 more source
CHEMOTHERAPY OF PNEUMOCOCCIC MENINGITIS WITH SPECIAL REFERENCE TO SULFATHIAZOLE [PDF]
F. B. Cooper+2 more
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Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi+11 more
wiley +1 more source
Advances in Intraperitoneal Chemotherapy for Gastric Cancer Patients with Peritoneal Metastases: Current Status of Treatment and Institutional Insights. [PDF]
Saito S+6 more
europepmc +1 more source
Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang+6 more
wiley +1 more source
Chemotherapy-related adverse drug reaction and associated factors among adult cancer patient attending Jimma medical center oncology unit, Southwest Ethiopia. [PDF]
Shrmeka MS+4 more
europepmc +1 more source