Results 281 to 290 of about 2,023,245 (348)

Self‐Assembling Multi‐Antigen T Cell Hybridizers for Precision Immunotherapy of Multiple Myeloma

Advanced Healthcare Materials, EarlyView.
A novel modular T‐cell engager platform, MATCH, is developed for personalized multiple myeloma therapy. MATCH uses complementary oligonucleotide‐linked Fab’ fragments to enable flexible targeting of MM antigens and controlled T‐cell activation. The system shows potent, antigen‐specific cytotoxicity in vitro and in vivo, highlighting its potential for ...
Shannuo Li, Jiahui Li, Hasan Al Faruque, Paul Shami, Birgit Knoechel, Jens Lohr, Douglas Sborov, Jiyuan Yang, Jindřich Kopeček   +8 more
wiley   +1 more source

Prophylactic Pegfilgrastim Versus On-Demand Filgrastim During Docetaxel and Cyclophosphamide Chemotherapy in Early-Stage Breast Cancer: A Retrospective Analysis. [PDF]

Cureus
Banno H, Fujii K, Ohashi W, Ozaki K, Saitou M, Ido M, Gotou M, Takahito A, Kousaka J, Nakano S.   +9 more
europepmc   +1 more source

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, J. Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

Evaluation of the cardiotoxicity risk based on the HFA-ICOS score in a group of sub-Saharan African women before breast cancer treatment by chemotherapy and/or radiotherapy: a cross-sectional study in a group of Cameroonian women. [PDF]

Cardiooncology
Nganou-Gnindjio CN, Okobalemba EA, Tasong LA, Zende AM, Elong JT, Tumtchou P, Mapoko BE, Metogo JA, Essiben F, Hamadou B.   +9 more
europepmc   +1 more source

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

Advanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier, Justin Christopher D'Antin, Gemma Julio, Anna Roig   +3 more
wiley   +1 more source

Impact of treatment patterns and sequencing on clinical and economic outcomes in patients with metastatic urothelial cancer: IMPACT UC II study. [PDF]

Oncologist
Bilen MA, Diessner B, White J, Murphy L, Nguyen A, Kirker M, Gharibian N, Morris V, Bhanegaonkar A.   +8 more
europepmc   +1 more source

Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery

Advanced Healthcare Materials, EarlyView.
This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo, Daniel Lozano, Antonio J. Salinas, María Vallet‐Regí   +3 more
wiley   +1 more source

Efficacy of single low-dose dexamethasone with NEPA for the 168 h prevention of highly or moderately emetogenic chemotherapy. [PDF]

Front Pharmacol
He Y, Lou F, Huang X, Zhang Y, Lin Q, Tan W, Chen Q, Ren X, Shi H, Xiao L.   +9 more
europepmc   +1 more source

Guides for Developing Hundreds of Novel Chiral MXenes and MBenes Nanosheets/Quantum Dots for Next‐Generation Chiral Engineered Biomaterials Applications

Advanced Healthcare Materials, EarlyView.
The emerging field of MXene/MBene materials has progressed rapidly, advancing diverse research fields, including biomedical engineering, biomedicine, agriculture, and the environment. This nanobiotechnology can tackle longstanding challenges in these areas.
Alireza Rafieerad, Ahmad Amiri
wiley   +1 more source

Cost-effectiveness analysis of Cadonilimab in first-line treatment of advanced HER2-negative gastric cancer or gastroesophageal junction cancer. [PDF]

Therap Adv Gastroenterol
Zhu K, Qin M, Pan Z, Huang J.
europepmc   +1 more source