Results 51 to 60 of about 82,973 (322)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
El artículo aborda la problemática de las relaciones entre los conocimientos matemáticos escolares y los extraescolares en un contexto específico de la educación rural: los alumnos jornaleros agrícolas migrantes.
Diana Violeta Solares Pineda +1 more
doaj +2 more sources
Sobre cheques y normas penales en conflicto. Balance de Discusiones 9 (2009)
El texto retoma el debate dado en Discusiones 9 alrededor del artículo de Juan Pablo Alonso “Normas penales y conflicto de deberes”. Tras presentar brevemente los argumentos del autor, analizo algunas ramificaciones de los temas tratados en ...
Santiago Roldán
doaj +1 more source
Financial settlement modes and corruption: Evidence from developed nations [PDF]
Using recent pooled data from several developed nations, the paper uniquely examines whether the composition of payment instruments has a bearing on the prevalence of corruption in a country.
Goel, Rajeev K., Mehrotra, Aaron
core
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Es un concepto comunmente aceptado que los protestos son instrumentos públicos o auténticos, otorgados con las solemnidades legales y autorizados por los competentes funcionarios.
Alberto Viada Lozano
doaj
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
En la actualidad nos encontramos ante la presencia de una tendencia de la actividad jurisdiccional colombiana encaminada a acudir a criterios objetivos de responsabilidad de los establecimientos bancarios por el incumplimiento de sus obligaciones ...
Jorge Alberto Padilla Sánchez +1 more
doaj +1 more source
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source

