Results 71 to 80 of about 81,212 (287)
Barnes Hospital Bulletin [PDF]
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1222/thumbnail ...
core +1 more source
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Since the 1980s the Chilean state has opted for a market-based education system by funding almost all education through vouchers paid to the schools chosen by parents. The private sector has expanded considerably.
Cristián Bellei
doaj +1 more source
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
The first part of the article calls attention to the operational problems and institutional features of Swiss banking, which are of special “practical” importance for the banking world.
R.S. SAYERS
doaj +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Aliança estratégica ou estratégia hegemônica? Conservadorismo entre os desfavorecidos
Este artigo analisa um fenômeno em plena expansão - o crescimento de sentimentos aparentemente conservadores entre grupos desprivilegiados. Um excelente exemplo desse tipo de fatos é o apoio estratégico a políticas neoliberais e neoconservadoras por ...
Apple Michael W.
doaj
La predicción inmediata de la actividad económica (es decir, hacer estimaciones del período actual), es conveniente porque la mayoría de las medidas tradicionales de actividad económica se realizan con rezagos sustanciales.
Carlos León, Fabio Ortega
doaj +1 more source
Nonbanks and risk in retail payments [PDF]
This paper documents the importance of nonbanks in retail payments in the United States and in 15 European countries and analyzes the implications of the importance and multiple roles played by nonbanks on retail payment risks.
anonymous
core

