Results 71 to 80 of about 81,212 (287)

Barnes Hospital Bulletin [PDF]

open access: yes, 1984
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1222/thumbnail ...

core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Lorsque le système de financement constitue le problème : l’expérience chilienne des chèques en éducation

open access: yesRevue Internationale d’Éducation de Sèvres, 2019
Since the 1980s the Chilean state has opted for a market-based education system by funding almost all education through vouchers paid to the schools chosen by parents. The private sector has expanded considerably.
Cristián Bellei
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Banking in Switzerland

open access: yesPSL Quarterly Review, 2014
The first part of the article calls attention to the operational problems and institutional features of Swiss banking, which are of special “practical” importance for the banking world.
R.S. SAYERS
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Aliança estratégica ou estratégia hegemônica? Conservadorismo entre os desfavorecidos

open access: yesEducação & Sociedade, 2003
Este artigo analisa um fenômeno em plena expansão - o crescimento de sentimentos aparentemente conservadores entre grupos desprivilegiados. Um excelente exemplo desse tipo de fatos é o apoio estratégico a políticas neoliberais e neoconservadoras por ...
Apple Michael W.
doaj  

Predicción inmediata de la actividad económica con datos de pagos electrónicos. Un enfoque de modelado predictivo

open access: yesRevista de Economía del Rosario, 2018
La predicción inmediata de la actividad económica (es decir, hacer estimaciones del período actual), es conveniente porque la mayoría de las medidas tradicionales de actividad económica se realizan con rezagos sustanciales.
Carlos León, Fabio Ortega
doaj   +1 more source

Nonbanks and risk in retail payments [PDF]

open access: yes
This paper documents the importance of nonbanks in retail payments in the United States and in 15 European countries and analyzes the implications of the importance and multiple roles played by nonbanks on retail payment risks.
anonymous
core  

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