Results 51 to 60 of about 81,212 (287)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
A Modern Writing Instrument Used as a Weapon for Committing Bank Cheque Fraud
Brazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2019 In the recent era, investigation of dye, pigments and powder-based ink examination are big challenges. Literature and survey reveal that, some erasable ink pens were consistently used to commit economic frauds in bank instruments like cheques, withdrawal
Vivekkumar Mangilal Chayal +5 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
tripleC: Communication, Capitalism & Critique, 2017 Internet memes play an important role in the reproduction, reinforcement and circulation of social stereotypes, including about those who live in poverty.
Kathy Dobson, Irena Knezevic
doaj +1 more source
Financial settlement modes and corruption: Evidence from developed nations [PDF]
Using recent pooled data from several developed nations, the paper uniquely examines whether the composition of payment instruments has a bearing on the prevalence of corruption in a country.
Goel, Rajeev K., Mehrotra, Aaron
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Revista de Derecho (Coquimbo), 2003 Es un concepto comunmente aceptado que los protestos son instrumentos públicos o auténticos, otorgados con las solemnidades legales y autorizados por los competentes funcionarios.
Alberto Viada Lozano
doaj
Sobre cheques y normas penales en conflicto. Balance de Discusiones 9 (2009)
Revista Discusiones, 2019 El texto retoma el debate dado en Discusiones 9 alrededor del artículo de Juan Pablo Alonso “Normas penales y conflicto de deberes”. Tras presentar brevemente los argumentos del autor, analizo algunas ramificaciones de los temas tratados en ...
Santiago Roldán
doaj +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source