Results 31 to 40 of about 2,366,294 (310)

Long‐Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Most adults presenting with chest pain will not receive a diagnosis and be recorded with unattributed chest pain. The objective was to assess if they have increased risk of cardiovascular disease compared with those with noncoronary chest pain
Kelvin P. Jordan, Trishna Rathod‐Mistry, James Bailey, Ying Chen, Lorna Clarson, Spiros Denaxas, Richard A. Hayward, Harry Hemingway, Danielle A. van der Windt, Mamas A. Mamas   +9 more
doaj   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source

Chest Pain Relieved with a Bronchodilator or Other Asthma Drugs

Allergology International, 2009
Background: Although many patients who experience chest pain or pressure consult their physicians, unfortunately a large number of them do not, and consequently they remain undiagnosed and untreated.
Hirokazu Taniguchi, Kenta Kanbara, Kiyoshi Hoshino, Saburo Izumi   +3 more
doaj   +1 more source

Daratumumab Treatment for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP): A Case Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an immune‐mediated neuropathy featuring progressive weakness, sensory deficits, and areflexia. While corticosteroids, intravenous immunoglobulin, and plasmapheresis are effective first‐line immunotherapies, a subset of patients remains treatment‐refractory.
Xueyu Zhang, Jianli Zhao, Xue Zhao, Xiaowei Hu, Zichun Xiao, Jie Wu, Xiaowen Li, Jing Xu, Yu‐Jing Li   +8 more
wiley   +1 more source

Vaspin alleviates pathological cardiac hypertrophy by regulating autophagy-dependent myocardial senescence

Emergency and Critical Care Medicine
. Background. Visceral adipose tissue–derived serine protease inhibitor (vaspin), a secretory adipokine, protects against insulin resistance. Recent studies have demonstrated that serum vaspin levels are decreased in patients with coronary artery disease
Haiying Rui, Huaxiang Yu, Dan Zou, Kai Chi, Ping Xu, Xiaoshuai Song, Lulu Liu, Xuting Wu, Jinxin Wang, Li Xue   +9 more
doaj   +1 more source

LOXHD1 and RHOB Expression by Monocytes Predicts Progressive Systemic Sclerosis associated Interstitial Lung Disease

Arthritis Care &Research, Accepted Article.
Objective A leading cause of death among scleroderma (SSc) patients, interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M Padilla, Robert Lafyatis, Kevin F Gibson, Christina Morse, Eleanor Valenzi, Xiaoping Chen, Xiaoyun Li, Yanwu Zhao, Yongseok Park, Dana Ascherman, Jonathan Minden, Robyn Domsic, Yingze Zhang, Daniel J Kass   +13 more
wiley   +1 more source

Early identification of sepsis-induced coagulopathy in critical ill patients: an analysis from MIMIC IV database

BMC Infectious Diseases
Background To develop a model for early identification of coagulopathy in septic patients. Methods Patients with sepsis were identified from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Patients who did not meet the sepsis-induced
Yiming Dong, Nana Cao, Jinlei Wu, Xilong Liu, Xuyang Ji, Xiaofei Yin, Shuo Wu, Bailu Wang, Shujian Wei, Yuguo Chen   +9 more
doaj   +1 more source

Intermittent Chest Pain

MedEdPORTAL, 2016
Introduction Deep T inversions in the anterior leads (Wellens' syndrome) are a sign of life-threatening coronary artery occlusion. The purpose of this simulation experience is to present a Wellens' syndrome case that allows medical students, emergency ...
Erin Schlossman, Megan Taylor, David Masneri   +2 more
doaj   +1 more source

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

Arthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

ALDH2 mediates the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on improving cardiac remodeling

Cardiovascular Diabetology
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are now recommended for patients with heart failure, but the mechanisms that underlie the protective role of SGLT2i in cardiac remodeling remain unclear.
Han Liu, Bingchen Jiang, Rui Hua, Xuehao Liu, Bao Qiao, Xiangxin Zhang, Xilong Liu, Wenjun Wang, Qiuhuan Yuan, Bailu Wang, Shujian Wei, Yuguo Chen   +11 more
doaj   +1 more source