Results 41 to 50 of about 414,205 (309)

Invasive treatment of NSTEMI patients in German chest pain units – evidence for a treatment paradox

, 2018
Background: Patients with non ST-segment elevation myocardial infarction (NSTEMI) represent the largest fraction of patients with acute coronary syndrome in German Chest Pain units. Recent evidence on early vs.
Münzel, Thomas, Maier, Lars S., Mudra, Harald, Darius, Harald, Claus Schmitt, Gerd Heusch, Maier, Lars Siegfried, Heusch, Gerd, Thomas Münzel, Harald Darius, Tommaso Gori, Harald Mudra, Schmitt, Claus, Hochadel, Matthias, Schmidt, Frank Patrick, Thomas Voigtländer, Gori, Tommaso, Evangelos Giannitsis, Giannitsis, Evangelos, Senges, Jochen, Voigtländer, Thomas, Schmidt, Frank P., Lars S. Maier, Frank P. Schmidt, Matthias Hochadel, Jochen Senges   +25 more
core   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Vaspin alleviates pathological cardiac hypertrophy by regulating autophagy-dependent myocardial senescence

Emergency and Critical Care Medicine
. Background. Visceral adipose tissue–derived serine protease inhibitor (vaspin), a secretory adipokine, protects against insulin resistance. Recent studies have demonstrated that serum vaspin levels are decreased in patients with coronary artery disease
Haiying Rui, Huaxiang Yu, Dan Zou, Kai Chi, Ping Xu, Xiaoshuai Song, Lulu Liu, Xuting Wu, Jinxin Wang, Li Xue   +9 more
doaj   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis–Associated Interstitial Lung Disease Risk

Arthritis Care &Research, EarlyView.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Early identification of sepsis-induced coagulopathy in critical ill patients: an analysis from MIMIC IV database

BMC Infectious Diseases
Background To develop a model for early identification of coagulopathy in septic patients. Methods Patients with sepsis were identified from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Patients who did not meet the sepsis-induced
Yiming Dong, Nana Cao, Jinlei Wu, Xilong Liu, Xuyang Ji, Xiaofei Yin, Shuo Wu, Bailu Wang, Shujian Wei, Yuguo Chen   +9 more
doaj   +1 more source

Emergency Department Admissions of Children with Chest Pain before and during COVID-19 Pandemic

Children, 2023
Objectives: We compared the number of accesses, causes, and instrumental evaluations of chest pain in children between the pre-COVID-19 era and the COVID-19 period and analyzed the assessment performed in children with chest pain, highlighting ...
Riccardo Lubrano, Vanessa Martucci, Alessia Marcellino, Mariateresa Sanseviero, Alessandro Sinceri, Alessia Testa, Beatrice Frasacco, Pietro Gizzone, Emanuela Del Giudice, Flavia Ventriglia, Silvia Bloise   +10 more
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

ALDH2 mediates the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on improving cardiac remodeling

Cardiovascular Diabetology
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are now recommended for patients with heart failure, but the mechanisms that underlie the protective role of SGLT2i in cardiac remodeling remain unclear.
Han Liu, Bingchen Jiang, Rui Hua, Xuehao Liu, Bao Qiao, Xiangxin Zhang, Xilong Liu, Wenjun Wang, Qiuhuan Yuan, Bailu Wang, Shujian Wei, Yuguo Chen   +11 more
doaj   +1 more source

Chest Pain Relieved with a Bronchodilator or Other Asthma Drugs

Allergology International, 2009
Background: Although many patients who experience chest pain or pressure consult their physicians, unfortunately a large number of them do not, and consequently they remain undiagnosed and untreated.
Hirokazu Taniguchi, Kenta Kanbara, Kiyoshi Hoshino, Saburo Izumi   +3 more
doaj   +1 more source