Results 31 to 40 of about 1,570,569 (245)

Vaspin alleviates pathological cardiac hypertrophy by regulating autophagy-dependent myocardial senescence

Emergency and Critical Care Medicine
. Background. Visceral adipose tissue–derived serine protease inhibitor (vaspin), a secretory adipokine, protects against insulin resistance. Recent studies have demonstrated that serum vaspin levels are decreased in patients with coronary artery disease
Haiying Rui, Huaxiang Yu, Dan Zou, Kai Chi, Ping Xu, Xiaoshuai Song, Lulu Liu, Xuting Wu, Jinxin Wang, Li Xue   +9 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Early identification of sepsis-induced coagulopathy in critical ill patients: an analysis from MIMIC IV database

BMC Infectious Diseases
Background To develop a model for early identification of coagulopathy in septic patients. Methods Patients with sepsis were identified from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Patients who did not meet the sepsis-induced
Yiming Dong, Nana Cao, Jinlei Wu, Xilong Liu, Xuyang Ji, Xiaofei Yin, Shuo Wu, Bailu Wang, Shujian Wei, Yuguo Chen   +9 more
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source

Chest Pain: Advanced Assessment and Management Skills

, 2008
Chest Pain: AdvancedAssessment and Management promotes a systematic approach to the assessment and management of patients presenting with chest pain and related undifferentiated symptoms.
Albarran, John W., Hoskins, Rebecca, Tagney, Jenny   +2 more
core   +1 more source

ALDH2 mediates the effects of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on improving cardiac remodeling

Cardiovascular Diabetology
Background Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are now recommended for patients with heart failure, but the mechanisms that underlie the protective role of SGLT2i in cardiac remodeling remain unclear.
Han Liu, Bingchen Jiang, Rui Hua, Xuehao Liu, Bao Qiao, Xiangxin Zhang, Xilong Liu, Wenjun Wang, Qiuhuan Yuan, Bailu Wang, Shujian Wei, Yuguo Chen   +11 more
doaj   +1 more source

Emergency Department Admissions of Children with Chest Pain before and during COVID-19 Pandemic

Children, 2023
Objectives: We compared the number of accesses, causes, and instrumental evaluations of chest pain in children between the pre-COVID-19 era and the COVID-19 period and analyzed the assessment performed in children with chest pain, highlighting ...
Riccardo Lubrano, Vanessa Martucci, Alessia Marcellino, Mariateresa Sanseviero, Alessandro Sinceri, Alessia Testa, Beatrice Frasacco, Pietro Gizzone, Emanuela Del Giudice, Flavia Ventriglia, Silvia Bloise   +10 more
doaj   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source

Coronary heart disease, healthcare policy and evolution of chest pain assessment and management in the UK

, 2020
Chest Pain: Advanced Assessment and Management promotes a systematic approach to the assessment and management of patients presenting with chest pain and ..
Quinn, TJ
core   +1 more source

Ofatumumab Therapy and Long‐Term Seizure Outcomes of Patients With Relapsing Anti‐NMDA Receptor Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There is a lack of studies on seizure outcomes associated with ofatumumab therapy in patients for relapsing anti‐N‐methyl‐D‐aspartate (NMDA) receptor encephalitis. We aimed to evaluate long‐term seizure outcomes of ofatumumab therapy for relapsing anti‐NMDA receptor encephalitis.
Jian Wang, Mengjiao Li, Ping Kong
wiley   +1 more source