Results 181 to 190 of about 126,182 (299)

Loncastuximab Tesirine in a Frail, Heavily Pretreated Patient With Relapsed/Refractory Diffuse Large B‐Cell Lymphoma: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Loncastuximab tesirine may offer a feasible, well‐tolerated option for frail, heavily pretreated patients with relapsed/refractory DLBCL and poor performance status when intensive therapies are unsuitable, achieving durable remission with manageable fluid retention through careful monitoring, spironolactone‐based treatment, and dose ...
Reyad Dada, Refaei Belal Ibrahim
wiley   +1 more source

Minimally Invasive Thoracoscopic Resection of a Giant Right‐Atrial Lipoma on the Beating Heart: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Primary cardiac lipomas are rare benign tumors that are usually indolent but may cause compression or arrhythmia when large. We sought to describe the safety and feasibility of a totally thoracoscopic, off‐pump approach for their resection. A 33‐year‐old asymptomatic woman was found to have a 5.1 × 3.6 cm fat‐density mass at the roof of the ...
Liang Zhou   +3 more
wiley   +1 more source

Meckel's Diverticulum Causing Sigmoid Knotting and Closed‐Loop Obstruction: A Rare Case Report From a Resource‐Limited Setting

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Meckel's diverticulum rarely causes large bowel obstruction through a fibrous band, leading to sigmoid knotting and closed‐loop gangrene. In patients presenting with acute intestinal obstruction without prior abdominal surgery, this etiology should be considered.
Biruk Umer Mohammed   +6 more
wiley   +1 more source

Bladder Outlet Obstruction Secondary to a Prostatic Cyst in a Young Adult: A Rare Case Report

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Bladder outlet obstruction secondary to an obstructing prostatic cyst is a rare clinical entity. Incomplete regression of the Müllerian duct is supposed to be the cause of such cysts. Clinical features can range from acute bladder outlet obstruction to chronic urinary retention, oligospermia, and prostatitis‐like symptoms.
Suraj K. C.   +3 more
wiley   +1 more source

“The Long Road to a Rare Destination”: Ovarian Serous Carcinoma With Late Thymic Metastasis 25 Years After Diagnosis

open access: yesClinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT We report a rare case of thymic metastasis of ovarian serous carcinoma. A 72‐year‐old woman who had undergone surgery for low‐grade serous carcinoma of the ovary and had been free of disease for 25 years was noted to have rising CA‐125 levels. Further workup revealed a mediastinal mass on imaging.
Nicole Fye   +3 more
wiley   +1 more source

Presence of IDH2 and TP53 mutations significantly reduces survival of patients with chondrosarcoma

open access: yesCancer, Volume 132, Issue 7, 1 April 2026.
Abstract Background Chondrosarcoma (CS) has a prognosis largely influenced by tumor grade. Although IDH mutations have been reported in CS, impact on patient`s survival remains controversial. This study aims to assess prognostic relevance of IDH mutations on disease‐specific survival (DSS), metastasis‐free survival (MFS), and local recurrence‐free ...
Anne Weidlich   +8 more
wiley   +1 more source

A Review of Vagus Nerve Stimulation for Disease: Comprehensive Theory and Evidence for Mechanisms of Action

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
Vagus nerve stimulation (VNS) effects span central and peripheral organ systems through diverse mechanistic pathways. This comprehensive review provides a unified synthesis of these mechanisms across neurological, cardiovascular, immunological, metabolic, and gastrointestinal domains, filling a critical gap and serving as a foundational resource for ...
Yifeng Bu   +11 more
wiley   +1 more source

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