Results 81 to 90 of about 6,019 (285)

Children chewable multivitamins : a general study

, 1995
Over the past decade, the use of vitamin supplements among children has been gaining popularity. The primary purpose of this report is, firstly, to highlight the various brands of children chewable multivitamins available in the market.
Tan, Sally Sock Li, Farah Sadiq, Tan, Joy Su-Mien   +2 more
core  

Preparation and in-Vitro Evaluation of Cinnarizine Raft Forming Chewable Tablets

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2019
Cinnarizine is an anti-histaminic drug and is mainly used to treat symptoms accompanying motion sickness like vomiting and dizziness. It has low and variable bioavailability due to its low water solubility.
Aseel S. Najm, Wedad K. Ali
doaj   +1 more source

Study Effect of Storage Temperature and Packaging Methods on Physical Characteristics of Gelatin-Based Moringa Leaf Extract Chewable Gummy [PDF]

, 2022
Moringa leaf extract potential to develop into nutraceutical products like chewable gummy because it contains the high activity of antioxidants. The optimal chewable gummy formula of Moringa leaf extract chewable gummy was obtained by using a 10% gelatin
Dewi, Syalza mumpuni, Rani, Karina Citra, Jayani, Nikmatul Ikhrom Eka   +2 more
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Medicated chewing gums - A novel targeted drug delivery

Journal of Indian Academy of Oral Medicine and Radiology, 2019
The potential of medicated chewing gum (MCG) for buccal delivery, fast onset of action makes it an attractive delivery form. It is considered as vehicle or a drug delivery system to administer active principles that can improve health and nutrition ...
Nimesh Jain, Manisha Jadhav, Rajeshwari G Annigeri, Pratik R Pipaliya   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Technological aspects of obtaining the chewable tablets with oats extract and quercetin

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2014
Aim. In the complex treatment of diseases that are associated with the stress or the overfatigue, much attention is paid to the drug therapy. On the Ukrainian pharmaceutical market synthetic drugs dominate among other drugs of tonic effect.
I. R. Andriichuk, L. L. Davtyan
doaj   +1 more source