Results 171 to 180 of about 97,651 (273)

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

Advanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin, Dilara Aylar, Archna Sharma, Ping Wang   +3 more
wiley   +1 more source

Efficacy of sarolaner in Simparica^® (sarolaner) chewables and Simparica Trio^® (sarolaner, moxidectin, and pyrantel chewable tablets) against two US strains of Haemaphysalis longicornis. [PDF]

Parasit Vectors
Rodriguez J, Jones S, Taylor L, DeMarco J, Baker K, Myers M.   +5 more
europepmc   +1 more source

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source

Comparative Bioavailability of Methylphenidate Powder for Prolonged-Release Oral Suspension and Methylphenidate Prolonged-Release Chewable Tablets versus Methylphenidate Immediate-Release Tablets: Phase 1, Single-Dose, Randomised, Crossover Studies in Healthy Adults. [PDF]

Clin Drug Investig
Ramos-Quiroga JA, Forcadell Ferré M, Schneider-Pérez A, Bouhajib M.   +3 more
europepmc   +1 more source

Extended Release Chewable Tablet [PDF]

, 2020
openaire   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

Efficacy of Natural β-Carotene Chewable Tablets Derived from Banana (<i>Musa</i> AA) Pulp in Reducing UV-Induced Skin Erythema. [PDF]

Nutrients
Putthong C, Panmanee T, Charoensit P, Ross S, Tongpoolsomjit K, Viyoch J.   +5 more
europepmc   +1 more source

THE EFFECT OF HPMC CONCENTRATION AS A BINDING AGENT ON THE PHYSICAL QUALITY EVALUATION OF CHEWABLE TABLETS CONTAINING RED GUAVA (Psidium guajava Linn) EXTRACT

Red guava fruit (Psidium guajava L.) contains flavonoid and tannin compounds that function as antioxidant. Red guava fruit extract can be formulated into chewable tablets because it provides a pleasant taste in the oral cavity and is easy to swallow. The
Firnanda, Shintia
core  

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Efficacy of Immunoglobulin Y Chewable Tablets on Streptococcus mutans Count in Patients Undergoing Orthodontic Treatment. [PDF]

Int J Clin Pediatr Dent
Muthukumaran M, Jayaprakash J, Arangannal P, Mahalakshmi K.   +3 more
europepmc   +1 more source