Results 31 to 40 of about 544,979 (256)

An Adaptive Filter for Image Noise Removal Using Chi-Square Goodness-of-Fit to Uniform Distribution [PDF]

open access: yesEngineering and Technology Journal, 2013
Noise is any undesired information that contaminates an image. The ideal situation (no noise) never occurs in practice, so there is a little point in ignoring it. Hence, one of the primary concerns of digital image processing is to increase image quality
Abdulameer A. Kareem   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Testing Multivariate Normality Based on F-Representative Points

open access: yesMathematics, 2022
The multivariate normal is a common assumption in many statistical models and methodologies for high-dimensional data analysis. The exploration of approaches to testing multivariate normality never stops.
Sirao Wang   +3 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Exact distribution of the sum of two correlated chi-square variables and its application

open access: yesKuwait Journal of Science, 2013
The exact distribution of the sum of two chi-square random variables is known if the variables are independent. We derive the exact distribution of the sum of two correlated chi-square variables when they are correlated through a bivariate chi-square ...
ANWAR H. JOARDER, M. HAFIDZ OMAR
doaj  

Biostatistics series module 4: Comparing groups - categorical variables

open access: yesIndian Journal of Dermatology, 2016
Categorical variables are commonly represented as counts or frequencies. For analysis, such data are conveniently arranged in contingency tables. Conventionally, such tables are designated as r × c tables, with r denoting number of rows and c denoting ...
Avijit Hazra, Nithya Gogtay
doaj   +1 more source

A Method of CHI-square Feature Selection Based on Probability [PDF]

open access: yesJisuanji gongcheng, 2016
Traditional CHI-square feature selection method does not take into account the category number of words in imbalanced data sets,the frequency of words,the intra-class and inter-class distribution of words,so that it fails to choose valid feature words ...
ZHANG Huiyi,XIE Yeming,YUAN Zhixiang,SUN Guohua
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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