Results 51 to 60 of about 544,979 (256)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

APPLICATION OF CHI SQUARE TEST IN MARKETING RESEARCH [PDF]

open access: yesAnnals of the University of Petrosani: Economics, 2017
The paper brings into focus the usefulness of chi square test in the field of marketing research. A chi square test represents a statistical tool based on the chi-square distribution of probability, which is easy to apply by a non-mathematician ...
CODRUȚA DURA, IMOLA DRIGĂ
doaj  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

Noise robust chi-square generative adversarial network

open access: yesTongxin xuebao, 2020
Aiming at the obvious difference of image quality generated by generative adversarial network under different noises,a chi-square generative adversarial network (CSGAN) was proposed.Combing the advantages of quantification sensitivity and sparse ...
Hongjun LI, Chaobo LI, Shibing ZHANG
doaj   +2 more sources

TESTING AND MONITORING THE RANDOMNESS OF d DIGIT NUMBER GAME VERIFICACIÓN Y MONITOREO DE LA ALEATORIEDAD DE LOS JUEGOS DE NÚMEROS DE d DÍGITOS

open access: yesRevista Colombiana de Estadística, 2010
This work is centered on testing the randomness of d-digit number game. It is usual that this problem is studied by the χ² test and other tests for independence of successive draws. However, these tests require of large sample sizes.
Gutiérrez-Pulido Humberto   +1 more
doaj  

Monte Carlo Simulation of a Modified Chi Distribution with Unequal Variances in the Generating Gaussians. A Discrete Methodology to Study Collective Response Times

open access: yesMathematics, 2020
The Chi distribution is a continuous probability distribution of a random variable obtained from the positive square root of the sum of k squared variables, each coming from a standard Normal distribution (mean = 0 and variance = 1).
Juan Carlos Castro-Palacio   +4 more
doaj   +1 more source

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