Results 61 to 70 of about 544,979 (256)
FEBS Open Bio, EarlyView.NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Nonparametric methods for the analysis of single-color pathogen microarrays
BMC Bioinformatics, 2010 Background The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, and host nucleic acid composition can each have a profound effect on signal ...
Hornig Mady +7 more
doaj +1 more source
The Distribution of Chi-Square [PDF]
Proceedings of the National Academy of Sciences, 1931 Wilson, Edwin B., Hilferty, Margaret M.
openaire +3 more sources
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
ITEGAM-JETIAIn the study, sample distributions (Normal, Chi-square, F), number of observations (100, 500, 1000, 10000) and class distribution rates (0.1, 0.2, 0.3, 0.4, 0.5) were evaluated.
Hussein Ali Attallah +2 more
doaj +1 more source
A New S2 Control Chart Using Multiple Dependent State Repetitive Sampling
IEEE Access, 2018 The combined application of multiple dependent state sampling and the repetitive group sampling (RGS) is an efficient sampling scheme for industrial process monitoring as it combines the advantages of both the sampling schemes.
Mansour Sattam Aldosari +4 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Tracking fluctuating targets in extremely heterogeneous clutter using amplitude information
The Journal of Engineering, 2019 This study analyses the radar fluctuating target detection in G(0)-distributed clutter using dynamic programming – track before detect (DP-TBD) algorithm. G(0)-distributed clutter is often used to fit the complex circumstances. The authors use chi-square
Feng Li +4 more
doaj +1 more source
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source