Results 61 to 70 of about 520,005 (257)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Nonparametric methods for the analysis of single-color pathogen microarrays

BMC Bioinformatics, 2010
Background The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, and host nucleic acid composition can each have a profound effect on signal ...
Hornig Mady, Palacios Gustavo, Hui Jeffrey, Quan Phenix-Lan, Conlan Sean, Jabado Omar J, Briese Thomas, Lipkin W Ian   +7 more
doaj   +1 more source

The Distribution of Chi-Square [PDF]

Proceedings of the National Academy of Sciences, 1931
Wilson, Edwin B., Hilferty, Margaret M.
openaire   +3 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

The Effect of Data Conversion Methods (Naive Bayes, C5.0 & Support Vector Machine) on the Performance of Classification Algorithms in Data Mining

ITEGAM-JETIA
In the study, sample distributions (Normal, Chi-square, F), number of observations (100, 500, 1000, 10000) and class distribution rates (0.1, 0.2, 0.3, 0.4, 0.5) were evaluated.
Hussein Ali Attallah, Ahmed Al-Asadi, Doctor, Sadeer Sadeq   +2 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A New S² Control Chart Using Multiple Dependent State Repetitive Sampling

IEEE Access, 2018
The combined application of multiple dependent state sampling and the repetitive group sampling (RGS) is an efficient sampling scheme for industrial process monitoring as it combines the advantages of both the sampling schemes.
Mansour Sattam Aldosari, Muhammad Aslam, Nasrullah Khan, Liaquat Ahmad, Chi-Hyuck Jun   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Tracking fluctuating targets in extremely heterogeneous clutter using amplitude information

The Journal of Engineering, 2019
This study analyses the radar fluctuating target detection in G(0)-distributed clutter using dynamic programming – track before detect (DP-TBD) algorithm. G(0)-distributed clutter is often used to fit the complex circumstances. The authors use chi-square
Feng Li, Bangsheng Zhuo, Xiangjun Peng, Miaomiao Cheng, Di Yao   +4 more
doaj   +1 more source