Results 61 to 70 of about 1,188,608 (310)

Kalman Filter Auto-tuning through Enforcing Chi-Squared Normalized Error Distributions with Bayesian Optimization [PDF]

, 2023
Zhaozhong Chen, Harel Biggie, Nisar Ahmed, Simon Julier, Christoffer Heckman   +4 more
openalex   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

APPLICATION OF CHI SQUARE TEST IN MARKETING RESEARCH [PDF]

Annals of the University of Petrosani: Economics, 2017
The paper brings into focus the usefulness of chi square test in the field of marketing research. A chi square test represents a statistical tool based on the chi-square distribution of probability, which is easy to apply by a non-mathematician ...
CODRUȚA DURA, IMOLA DRIGĂ
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

The Modification of Chi-Square Tests for the Identification of Rainfall and River Flow Data Distribution [PDF]

, 2023
Heri Sulistiyono, I Wayan Yasa, Ery Setiawan, Hendra Ahyadi, Supardi Supardi, Husnulhuda Bajsair   +5 more
openalex   +1 more source

On some problems involving Hardy's function

, 2010
Some problems involving the classical Hardy function $$ Z(t) := \zeta(1/2+it)\bigl(\chi(1/2+it)\bigr)^{-1/2}, \quad \zeta(s) = \chi(s)\zeta(1-s) $$ are discussed.
A. Ivić, A. Ivić, A. Ivić, A. Ivić, A. Ivić, A. Ivić, A. Selberg, A.M. Odlyzko, Aleksandar Ivić, D.A. Hejhal, D.R. Heath-Brown, D.R. Heath-Brown, E.C. Titchmarsh, H.L. Montgomery, J.L. Hafner, J.L. Hafner, J.P. Keating, K. Ramachandra, M. Jutila, M.A. Korolëv   +19 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Conserved system with limited number of entities obeying non-Maxwellian, non-Gaussian and non-chi-square distributions

, 2020
We demonstrate that the most probable state of a conserved system with limited number of entities is the state where non-Maxwellian, non-Gaussian and non-chi-square distributions govern.
Shim, Jae Wan
core