Results 61 to 70 of about 8,833,133 (301)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Chi-square test result of the total error count by institution.
, 2023 Chi-square test result of the total error count by institution.
Wona Choi (13110145) +5 more
core +1 more source
Risk factors associated with glaucoma status: a case study of Abesim Health Center (2019-2021)
Russian Open Medical JournalBackground — Despite glaucoma being a global public health concern, there is currently no clear and accepted explanation for the causes of glaucoma. The National Blindness Survey conducted in Ghana shows that over 19% of blindness in Ghana was accounted ...
Kennedy Mensah +3 more
doaj +1 more source
Declining Trend of Water Inflow in the Dams of Rajasthan State
International Journal of Technology, 2014 Rajasthan is a semi arid state with the highest of the geographical area (343,000.00 square km) of the Indian subcontinent. Annual rainfall variation is very high over the state ranging from 100 mm to 1000 mm from west to south/east.
N.K. Gupta, A.S. Jethoo
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Tutorial on Bonferroni Correction as a Post Hoc Analysis of a Significant Chi-Squared Test: A Methodological Guide in Food Science [PDF]
Journal of Food Quality and Hazards ControlBackground: In medical research, analyzing the relationship between two categorical variables is common. While chi-square tests (e.g., Pearson's, McNemar's, and Cochran-Mantel-Haenszel) can determine if a significant association exists, they do not ...
F. Madadizadeh, M. Abdoli
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
, 2023 Chi-square test for association of sociodemographic and clinical variables with delayed sputum smear conversion.
Sarah Michael S. Liansim (14725366) +7 more
core +1 more source