Results 151 to 160 of about 6,315 (185)
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Some characteristics of myotubes cultured from slow and fast chick muscles
Journal of Cellular Physiology, 1974AbstractExplant cultures were prepared from the slow anterior latissimus dorsi muscle and the fast posterior latissimus dorsi muscle of 15 day chick embryos. The morphology and growth pattern of myotubes from the two types of muscle were very similar. Intracellular microelectrode studies did not reveal consistent differences between the myotube types ...
R D, Purves, G, Vrbová
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Block of single acetylcholine-activated channels in chick myotubes by alkylguanidines
Pfl�gers Archiv European Journal of Physiology, 1986The mechanism of block of single acetylcholine-activated channels by alkylguanidines was studied by means of the gigaohm seal, patch clamp technique on chick myotubes. The single channel current-voltage relationship in symmetrical Cs solutions was linear over membrane potentials from -100 mV to +100 mV with the reversal potential close to 0 mV.
J M, Farley, S M, Vogel, T, Narahashi
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Oxotremorine Acts as a Partial Nicotinic Agonist on Cultured Chick Myotubes
Acta Pharmacologica et Toxicologica, 1985Abstract:Oxotremorine, a compound widely used as a muscarinic agonist, was found to inhibit binding of125I–α–bungarotoxin to chick myotube nicotinic acetylcholine receptors, IC50 = 79 ± 5 μM. Oxotremorine also induced a d–tubocurarine sensitive influx of86Rb in the myotubes (EC50 = 50 ± 15 μM).
J, Häggblad, H, Eriksson, E, Heilbronn
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Location of endoplasmic reticulum relative to sarcoplasmic reticulum in cultured chick myotubes
Biochemical Society Transactions, 1997Calcium plays a major role as a second messenger modulating a wide range of cellular processes (1). Endoplasmic and sarcoplasmic reticulum calcium pumps (SERCAs) play a major role in controlling the levels of cytoplasmic calcium but the way in which these pumps are targeted to and maintained in specific cellular compartments is unclear.
I D, van Goethem +4 more
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Neuroscience Letters, 1996
Calcitonin gene-related peptide (CGRP), a neuropeptide may play a role in the formation of neuromuscular junctions is synthesized by the motor neurons and is able to stimulate the expression of acetylcholine receptor (AChR) in cultured myotubes.
Choi, Roy Chi Yan +4 more
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Calcitonin gene-related peptide (CGRP), a neuropeptide may play a role in the formation of neuromuscular junctions is synthesized by the motor neurons and is able to stimulate the expression of acetylcholine receptor (AChR) in cultured myotubes.
Choi, Roy Chi Yan +4 more
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Neuroscience Letters, 1987
In striated muscle, adenosine-5'-triphosphate (ATP) potentiates the responses to acetylcholine. The underlying biochemical events are unknown. Here we report that ATP, externally applied to chick myotubes, induces a rapid, dose-dependent accumulation of intracellular inositol triphosphate which is correlated with a decrease in phosphatidyl 4,5 ...
J, Häggblad, E, Heilbronn
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In striated muscle, adenosine-5'-triphosphate (ATP) potentiates the responses to acetylcholine. The underlying biochemical events are unknown. Here we report that ATP, externally applied to chick myotubes, induces a rapid, dose-dependent accumulation of intracellular inositol triphosphate which is correlated with a decrease in phosphatidyl 4,5 ...
J, Häggblad, E, Heilbronn
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Chick myotubes in culture express high-affinity receptors for calcitonin gene-related peptide
Brain Research, 1989Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide that is expressed by many neurons of the vertebrate nervous system, including motoneurons of many species. It has been detected immunohistochemically in both cell bodies and motor terminals of motoneurons, suggesting that it may play a role at the neuromuscular junction.
C G, Jennings, A W, Mudge
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The cAMP-dependent protein kinase mediates the expression of AChE in chick myotubes
NeuroReport, 2000Calcitonin gene-related peptide (CGRP), a neuropeptide synthesized by motor neurons, stimulates the expression of AChR and AChE at the vertebrate neuromuscular junctions. The signaling mechanism of CGRP-induced AChE expression in muscle was determined both in vitro and in vivo. In cultured chick myotubes, the intracellular cAMP-dependent protein kinase
Choi, Roy Chi Yan +3 more
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[3H]-nitrendipine binding in chick myotubes developing in culture.
Pharmacology, 1988Binding studies with the [3H]-nitrendipine were performed in homogenates of chick skeletal myotubes developing in culture. The specific binding data suggested two classes of binding sites with high and low affinities for nitrendipine. No significant changes in the dissociation constants of both high- and low-affinity sites could be detected over the ...
R, Satoh, M, Kano
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International Journal of Developmental Neuroscience, 1989
AbstractThe role of the electrogenic Na+‐K+ pump in the determination of the level of the resting membrane potential in cultured chick limb muscle was investigated. Transmembrane resting potential and ouabain‐sensitive86Rb‐uptake were measured in myotubes at different ages in culture from 2 to 10 daysin vitro. Inhibition of the Na+‐K+ pump with ouabain
C, Brodie, S R, Sampson
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AbstractThe role of the electrogenic Na+‐K+ pump in the determination of the level of the resting membrane potential in cultured chick limb muscle was investigated. Transmembrane resting potential and ouabain‐sensitive86Rb‐uptake were measured in myotubes at different ages in culture from 2 to 10 daysin vitro. Inhibition of the Na+‐K+ pump with ouabain
C, Brodie, S R, Sampson
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