Results 71 to 80 of about 6,315 (185)
Advanced Science, Volume 11, Issue 31, August 21, 2024.In this study, a hiPSC‐derived 3D tissue‐engineered model of LGMD2B skeletal muscle is developed and applied to show that calcium handling abnormalities drive multiple contractile and metabolic deficits in dysferlinopathy. This human in vitro model replicates transcriptional signatures and drug responses of diseased muscles from patients and small ...
Alastair Khodabukus +9 more
wiley +1 more source
Clustering of nicotinic acetylcholine receptors: from the neuromuscular junction to interneuronal synapses [PDF]
, 2018 Fast and accurate synaptic transmission requires high-density accumulation of neurotransmitter receptors in the postsynaptic membrane. During development of the neuromuscular junction, clustering of acetylcholine receptors (AChR) is one of the first ...
Fuhrer, C., Huh, K H.
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Advanced Science, Volume 11, Issue 26, July 10, 2024.This study describes the new generation laminin fragments, a recombinant form of a laminin E8 fragment conjugated to the heparan sulfate chains. Taking advantage of the new generation laminin fragments, authors established a highly efficient and xeno‐free protocol for paraxial mesoderm differentiation of hiPSCs followed by high myogenic induction ...
Mingming Zhao +10 more
wiley +1 more source
Endogenous mammalian lectin localized extracellularly in lung elastic fibers. [PDF]
, 1984 An affinity-purified antibody preparation raised against a beta-galactoside-binding lectin from bovine lung was used to localize a similar lectin in rat lung by immunofluorescence and by electron microscopy after on-grid staining visualized with ...
Barondes, SH +2 more
core +3 more sources
Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality? [PDF]
, 2011 Motor neuron diseases (MND) such as amyotrophic lateral sclerosis and spinal muscular atrophy are devastating, progressive and ultimately fatal diseases for which there are no effective treatments. Recent evidence from systematic studies of animal models
Amabile +72 more
core +1 more source
Extracellular matrix and integrins influence in the regulation of myogenic precursor cells behaviour [PDF]
, 2009 Tese de mestrado, Biologia (Biologia Molecular Humana), 2009, Universidade de Lisboa, Faculdade de CiênciasMyogenesis is the process by which undifferentiated dermomyotomal cells are specified for myogenesis, move towards the myotome where they ...
Vaz, Raquel Rodrigues
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Extended 2D myotube culture recapitulates postnatal fibre type plasticity [PDF]
, 2015 Background: The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the ability of myotubes to undergo ...
AG Guex +39 more
core +2 more sources
Acetylcholine Receptors and Concanavalin A-Binding Sites on Cultured Xenopus Muscle Cells: Electrophoresis, Diffusion, and Aggregation [PDF]
, 1988 Using digitally analyzed fluorescence videomicroscopy, we have examined the behavior of acetylcholine receptors and concanavalin A binding sites in response to externally applied electric fields.
Fraser, Scott E., Stollberg, Jes
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Establishing laboratory standards for biological flight experiments [PDF]
The general objective of this research was to assess the effects of exposure to simulated microgravity on ultrastructural aspects of the contractile system in chicken skeletal muscle cells. This general objective had two specific experimental components:
Moriarity, Debra M., Young, Ronald B.
core +1 more source