RNA splicing factor RBFOX2 is a key factor in the progression of cancer and cardiomyopathy
Clinical and Translational Medicine, Volume 14, Issue 9, September 2024.RNA‐binding fox‐1 homologue 2 (RBFOX2) binds to RNA, influencing splicing and recruiting PRC2 for transcriptional repression. RBFOX2 impacts electromyographic signalling, L‐type Ca2+ channels, sliding filaments and mitochondria. RBFOX2 is involved in tumour cell proliferation, invasion, migration and drug resistance.
Jinze Shen +4 more
wiley +1 more source
Local Accumulation of Acetylcholine Receptors is Neither Necessary Nor Sufficient to Induce Cluster Formation [PDF]
, 1990 Acetylcholine receptors (AChRs) accumulate at developing neuromuscular junctions in part via lateral migration of diffusely expressed receptors. Using a model system--cultured Xenopus muscle cells exposed to electric fields--we have shown that AChRs ...
Fraser, Scott E., Stollberg, Jes
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Clustering of nicotinic acetylcholine receptors: from the neuromuscular junction to interneuronal synapses [PDF]
, 2018 Fast and accurate synaptic transmission requires high-density accumulation of neurotransmitter receptors in the postsynaptic membrane. During development of the neuromuscular junction, clustering of acetylcholine receptors (AChR) is one of the first ...
Fuhrer, C., Huh, K H.
core
Developing cardiac and skeletal muscle share fast-skeletal myosin heavy chain and cardiac troponin-I expression [PDF]
, 2012 Skeletal muscle derived stem cells (MDSCs) transplanted into injured myocardium can differentiate into fast skeletal muscle specific myosin heavy chain (sk-fMHC) and cardiac specific troponin-I (cTn-I) positive cells sustaining recipient myocardial ...
A Du +39 more
core +3 more sources
Establishing laboratory standards for biological flight experiments [PDF]
The general objective of this research was to assess the effects of exposure to simulated microgravity on ultrastructural aspects of the contractile system in chicken skeletal muscle cells. This general objective had two specific experimental components:
Moriarity, Debra M., Young, Ronald B.
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Development and progress of engineering of skeletal muscle tissue [PDF]
, 2009 Engineering skeletal muscle tissue remains still a challenge, and numerous studies have indicated that this technique may be of great importance in medicine in the near future.
Liao, H, Zhou, GQ
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Molecular Oncology, Volume 19, Issue S1, Page 1-940, June 2025.Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source
Acetylcholine Receptors and Concanavalin A-Binding Sites on Cultured Xenopus Muscle Cells: Electrophoresis, Diffusion, and Aggregation [PDF]
, 1988 Using digitally analyzed fluorescence videomicroscopy, we have examined the behavior of acetylcholine receptors and concanavalin A binding sites in response to externally applied electric fields.
Fraser, Scott E., Stollberg, Jes
core
Extended 2D myotube culture recapitulates postnatal fibre type plasticity [PDF]
, 2015 Background: The traditional problems of performing skeletal muscle cell cultures derived from mammalian or avian species are limited myotube differentiation, and transient myotube persistence which greatly restricts the ability of myotubes to undergo ...
AG Guex +39 more
core +2 more sources
Review: Dystroglycan in the Nervous System [PDF]
, 2007 Dystroglycan is part of a large complex of proteins, the dystrophin-glycoprotein complex, which has been implicated in the pathogenesis of muscular dystrophies for a long time.
Matthias Samwald
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