Results 91 to 100 of about 5,468 (167)
ABSTRACT The COVID‐19 pandemic caused a crisis that jeopardized food consumption and dietary diversity. This study aimed to: (1) investigate relationship between COVID‐19 and women's and children's diets in India; (2) examine how this varies by socioeconomic status and mothers' vegetarianism; and (3) assess whether mobility restrictions during India's ...
Anjali Pant +4 more
wiley +1 more source
Abstract Background Acute pain transfusion reaction (APTR) is a rare, under‐recognized condition of unknown etiology. It can cause significant distress in recipients, necessitating symptomatic management and, occasionally, hospitalization. Study Design and Methods Here, we present an APTR event in an adult subject with transfusion‐dependent thalassemia
Georgia Tzafa +20 more
wiley +1 more source
Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats
Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North +3 more
wiley +1 more source
Diagnosis and epidemiology of chicken infectious anemia in Africa
Chicken infectious anemia (CIA) has recently emerged as an important disease problem in some of Africa’s major poultry-producing countries. Economic losses due to this disease arises from poor growth, increased mortality, carcass condemnations and the cost of antibiotics used to control secondary bacterial infections.
openaire +1 more source
Abstract figure legend This review utilized animal models of complicated human pregnancies that result in reduced fetal nutrient or oxygen delivery, or combined nutrient and oxygen delivery, to elucidate their independent and/or synergistic contributions to the development of high‐risk cardiac phenotypes.
Melanie R. Bertossa +8 more
wiley +1 more source
ABSTRACT Management of cerebral vasculopathy in sickle cell anemia (SCA) includes standard‐care, that is, chronic transfusion (CT) or hydroxyurea, and hematopoietic cell transplantation (HCT). DREPAGREFFE‐1 (December 2010/June 2013), a French multicenter trial, was the first prospective trial comparing standard‐care to match sibling donor (MSD)‐HCT in ...
Francoise Bernaudin +40 more
wiley +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi +4 more
wiley +1 more source
The function of bromodomain‐containing proteins in regulating gene transcription is reviewed here, including the development of chemical probes and targeted protein degradation modalities (e.g., PROTACs). This extends to clinical efforts targeting the BET bromodomain‐containing proteins. Challenges of selectivity, future prospects, and the differential
Cole R. Scholtz, William C. K. Pomerantz
wiley +1 more source
Efficacy and Safety of Low‐Frequency Daratumumab Regimen in Systemic Light‐Chain Amyloidosis
ABSTRACT In recent years, daratumumab has been increasingly applied in the treatment of systemic light‐chain (AL) amyloidosis, significantly improving the prognosis of patients. Currently, the internationally recognized daratumumab treatment regimen comes from the ANDROMEDA trial.
Jintao Lin +18 more
wiley +1 more source

