Results 61 to 70 of about 5,468 (167)

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

Journal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit, Marilena Vered, Michael Saminsky, Liat Chaushu   +3 more
wiley   +1 more source

Survey of primultaneous Contamination with CIAV and infection with AI and ND in broiler chicken of Chaharmahal - va - Bakhtiari provence [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2013
The agent of chicken infectious anemia (CIA) belongs to Circoviridae. CIA can cause severe anemia, immunosuppression and high sensitivity to bacterial, viral, parasitic and fungal pathogens. The aim of this study was to investigate simultaneous infection
ezzatollah fathihafshanjani
doaj  

A multiplex xTAG assay for the simultaneous detection of five chicken immunosuppressive viruses

BMC Veterinary Research, 2018
Background Chicken anemia virus (CAV), avian reovirus (ARV), infectious bursal disease virus (IBDV), Marek’s disease virus (MDV) and reticuloendotheliosis virus (REV) all cause immunosuppressive disease in birds through vertical or horizontal ...
Feng Cong, Yujun Zhu, Jing Wang, Yuexiao Lian, Xiangnan Liu, Li Xiao, Ren Huang, Yu Zhang, Meili Chen, Pengju Guo   +9 more
doaj   +1 more source

A Refractory Leg Skin Ulcer Associated With Multiple Myeloma Successfully Treated With Plasma Exchange, Lenalidomide, and Dexamethasone

JEADV Clinical Practice, EarlyView.
ABSTRACT Multiple myeloma (MM) is a malignant plasma cell disorder that primarily presents with CRAB symptoms (calcium elevation, renal failure, anemia, and bone abnormalities). In rare cases, MM manifests with systemic complications like skin ulcers, which present management challenges. Here, we report a 78‐year‐old Japanese man with MM and refractory
Naoko Hattori, Yutaka Kuwatsuka, Tomoka Waseda, Daisuke Ehara, Koji Ando, Hiroyuki Murota   +5 more
wiley   +1 more source

THE EFFECT OF NEEM LEAVES EXTRACT AS IMMUNSTIMULANT BEFORE CHICKEN INFECTIOUS ANEMIA VACCINATION IN BROILERS

Slovenian Veterinary Research, 2023
Chicken infectious anemia (CIA) has lately arisen as a major problem in poultry production due to poor growth, high mortalities. We successfully used PCR on seven flocks of chickens (three breeder and four broiler) in the Egyptian governorates of ...
Ahmed M. E. Hegazy, Ahmed M. Kamel, Ibrahim F. Rehan, Hala M. N. Tolba   +3 more
doaj   +1 more source

Alopecia Areata in a Patient Receiving Cemiplimab for Metastatic Cutaneous Squamous Cell Carcinoma

JEADV Clinical Practice, EarlyView.
ABSTRACT Introduction Alopecia areata (AA) is an autoimmune disease characterized by non‐scarring hair loss of the scalp and/or body, with an unpredictable and variable clinical course. Its etiology is not entirely understood, although evidence suggests that environmental, immunological, and genetic factors contribute to disease development.
Marco Rubatto, Eleonora Bongiovanni, Veronica Arese, Michela Camilla Milanesio, Alessia Reali, Massimo Chiarpenello, Gianmauro Numico, Marcella Occelli   +7 more
wiley   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

TRANSMISSIBLE VIRAL PROVENTRICULITIS AND STUNTING SYNDROME IN BROILER CHICKENS IN EGYPT: 1. ISOLATION AND CHARACTERIZATION OF VARIANT INFECTIOUS BURSAL DISEASE VIRUS (IBDV) [PDF]

Veterinary Medical Journal - Giza, 2003
In the present study, 46 broiler chicken flocks (2 to 4 weeks of age and in farms located in four governorates were examined. They were affected with proventriculitis and stunting syndrome and were vaccinated with classical infectious bursal disease ...
HA HUSSEIN, A ALY, H SULTAN, M AL-SAFTY
doaj   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source