Results 71 to 80 of about 202,423 (312)
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Impact of Rotten Eggs on Hatchery Performances: A Multicentric Study
Animals, 2020 Day-old chick quality is an essential element for the overall profitability of the broiler productive cycle and has been associated with the growth performance and feed conversion rate. An effect on the development of the immune system was also reported,
Giovanni Franzo +7 more
doaj +1 more source
Extensive microbial and functional diversity within the chicken cecal microbiome [PDF]
, 2014 Chickens are major source of food and protein worldwide. Feed conversion and the health of chickens relies on the largely unexplored complex microbial community that inhabits the chicken gut, including the ceca.
Sergeant Martin J. +33 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Poultry Science, 1971 Abstract Briggs and King (1952) perfected a method for transferring nuclei of embryonic cells into enucleated eggs of the frog. Gurdon (1960) described a method by which he obtained many genetically identical frogs by the direct and serial transplantation of the nuclei of dissociated endoderm cells to the enucleated eggs of a single female. The cells
P S, Fiser, F N, Jerome
openaire +2 more sources
Development and evaluation of DNA vaccines in chickens against a wild bird H6N2 avian influenza virus from Western Australia [PDF]
, 2010 Genetic immunization, also known as DNA or polynucleotide immunisation, is well documented to induce broad-based immunity in various animal models of infectious and non-infectious diseases.
Shan, Songhua
core
Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]
, 2002 Interleukin-2 (IL-2) exercises an array of biological effects on many cells including the functional activation of cells of the innate immune response.
Pete Kaiser +5 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Toxins, 2020 The aim of this study was to investigate the protective effects of selenium yeast (Se-Y) against hepatotoxicity induced by ochratoxin A (OTA). The OTA-induced liver injury model was established in chickens by daily oral gavage of 50 µg/kg OTA for 21
Peng Li +7 more
doaj +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source