Results 71 to 80 of about 5,196,912 (292)
A Case of Paraganglioma as an Unusual Tenant of Gallbladder [PDF]
Gallbladder paraganglioma is an exceptionally uncommon tumour. Paragangliomas are a subset of Neuroendocrine Neoplasms (NENs) called neurogenic NENs that arise from neural crest cells of the neuroectoderm.
Snehlata Hingway +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Secretion of Intrinsic Factor from Cultured Rat Gastric Chief Cells [PDF]
Intrinsic factor (IF) is a vitamin B12 binding protein that is secreted from the gastric mucosa. We tested secretagogues which stimulate IF secretion in rat gastric perfusion and found that carbachol and cholecystokinin octapeptide (CCK-8) stimulated ...
谷, 覺 +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Office of Chief Medical Examiner
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed May 24, 2011).; At head of title: State of Connecticut.; Harvested from the web on 5/24/11Official website of the Office of the Chief Medical Examiner.
core
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Video footage from the WBAP-TV television station in Fort Worth, Texas, to accompany a news story about Dallas' police chief resigning and being replaced by assistant chief Jess ...
WBAP-TV (Television station : Fort Worth, Tex.)
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The typical sonomorphology of homogeneously hypoechoic texture of an enlarged parathyroid gland (PG) is a reflection of uniform arrangement of the parathormone-producing chief cells.
Yashant Aswani +3 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
The disappearing chief cell phenomenon (DCP): A preliminary report
Abstract The appearance of chief cells was studied in normal dogs and in dogs after anterior and bilateral highly selective vagotomy. The normal chief cell is columnar in shape, with a well-defined cell membrane, basal nucleus and basophilic cytoplasm. Many cells show what has been called the ‘disappearing chief cell phenomenon’—DCP. The
openaire +2 more sources

