Results 91 to 100 of about 89,546 (321)

Long lasting anti-IgG chikungunya seropositivity in the Mayotte population will not be enough to prevent future outbreaks: A seroprevalence study, 2019.

PLoS ONE, 2023
Chikungunya is an arboviral disease causing arthralgia which may develop into a debilitating chronic arthritis. In Mayotte, a French overseas department in the Indian Ocean, a chikungunya outbreak was reported in 2006, affecting a third of the population.
Giuseppina Ortu, Gilda Grard, Fanny Parenton, Marc Ruello, Marie-Claire Paty, Guillaume André Durand, Youssouf Hassani, Henriette De Valk, Harold Noël, Unono Wa Maore group   +9 more
doaj   +1 more source

Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry

ChemMedChem, EarlyView.
This review highlights the rationale behind multitarget drug design as a promising approach to address diseases with complex etiologies. By combining pharmacophore features from different single‐target drugs, multitarget compounds can interact with multiple biological targets simultaneously.
Sadık Hüseyin Cemali, Samet Poyraz, Samet Belveren, Senanur Taş, Mehmet Ali Tamer, Naciye Yaktubay Döndaş, H. Ali Döndaş, Jose Miguel Sansano   +7 more
wiley   +1 more source

Historical Patterns of Arboviral Seroprevalence across Africa and Asia [PDF]

, 2017
The emergence and resurgence of arboviruses in recent history is challenging our scientific understanding of mosquito-borne diseases and their transmission.
Chrisafis, George C
core   +1 more source

Zika virus infection in the returning traveller: what every neurologist should know [PDF]

, 2018
Zika virus has been associated with a wide range of neurological complications. Neurologists in areas without current active transmission of the virus may be confronted with Zika-associated neurological disease, as a large number of returning travellers ...
Brito Ferreira, Maria Lucia, Jacobs, Bart C., Lant, Suzannah, Leonhard, Sonja Emily, Solomon, Tom, Wilder-Smith, Annelies, Willison, Hugh   +6 more
core   +5 more sources

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules

Immunity, Inflammation and Disease
Background Pattern recognition receptors (PRRs) are the receptors of the innate immune system that play a vital role in initiating innate immune response.
Meenal Sharma, Priyanka Wagh, Tanvi Shinde, Diptee Trimbake, Anuradha S. Tripathy   +4 more
doaj   +1 more source

Equine Polyclonal Antibodies Prevent Acute Chikungunya Virus Infection in Mice

Viruses, 2023
Chikungunya virus (CHIKV) is a mosquito-transmitted pathogen that causes chikungunya disease (CHIK); the disease is characterized by fever, muscle ache, rash, and arthralgia.
Douglas Barker, Xiaobing Han, Eryu Wang, Ashley Dagley, Deborah M. Anderson, Aruni Jha, Scott C. Weaver, Justin Julander, Cory Nykiforuk, Shantha Kodihalli   +9 more
doaj   +1 more source

Phytochemistry, pharmacological insights, and food science applications of natural bioactive compounds from Ocimum species with a focus on essential oils

Food Frontiers, EarlyView.
The article examines the phytochemistry, pharmacology, and food science applications of essential oils and extracts from Ocimum species (basil). It covers diverse extraction methods like hydrodistillation and microwave‐assisted extraction while discussing pharmacological benefits.
Oberdan Oliveira Ferreira, Ravendra Kumar, Luiz Renan Ramos da Silva, Suraj N. Mali, Srushti Tambe, Ulisses Alves Rosa, Leonardo Souza Costa, Lohren Glendha Nunes Lobato, Anderson de Santana Botelho, Himani Karakoti, Sonu Kumar Mahawer, Marcilene Paiva da Silva, Mozaniel Santana de Oliveira, Eloisa Helena de Andrade Aguiar   +13 more
wiley   +1 more source

A Metapopulation Model for Chikungunya Including Populations Mobility on a Large-Scale Network

, 2012
In this work we study the influence of populations mobility on the spread of a vector-borne disease. We focus on the chikungunya epidemic event that occurred in 2005-2006 on the R\'eunion Island, Indian Ocean, France, and validate our models with real ...
Arino, Arino, Auger, Bacaër, Balcan, Colizza, Cosner, Cui, Delatte, Djamila Moulay, Dumont, Dushoff, Fitzgibbon, González, Gratz, Hackett, Levins, Lloyd, Longini, Martens, Menach, Moulay, Moulay, Murray, Nishida, Ross, Rvachev, Sattenspiel, Smith, Sutherst, Vazeille, Wang, Yoann Pigné   +32 more
core   +2 more sources

Mapping of Aedes albopictus abundance at a local scale in Italy [PDF]

, 2017
Given the growing risk of arbovirus outbreaks in Europe, there is a clear need to better describe the distribution of invasive mosquito species such as Aedes albopictus. Current challenges consist in simulating Ae. albopictus abundance, rather than its
Arnoldi, Daniele, Baldacchino, Frédéric, Capelli, Gioia, Delucchi, Luca, Manica, Mattia, Marcantonio, Matteo, Marini, Giovanni, Montarsi, Fabrizio, Rizzoli, Annapaola, Rosà, Roberto, Zorer, Roberto   +10 more
core   +2 more sources

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source