Results 71 to 80 of about 55,640 (226)
Dimerization of human PARP15 is required for NAD+ binding and automodification
The FEBS Journal, EarlyView.This study provides an integrated structural model of human PARP15. Biophysical, enzymatic, and cell‐based analyses identify the dimer as the active oligomeric state capable of binding the substrate NAD+. A co‐crystal structure with a non‐hydrolyzable substrate analog BAD reveals the molecular basis for the dimerization requirement.
Anna Tuovinen +9 more
wiley +1 more source
Saintika Medika, 2018 Latarbelakang. Chikungunya merupakan salahsatu penyakit infeksi dengan gejala demam, nyeri sendi, dan ruam yang disebabkan oleh virus chikungunya (CHIKV) dan ditularkan melalui gigitan nyamuk.
David Budi Lukito +3 more
doaj +1 more source
International Statistical Review, EarlyView.Summary Understanding the spread of infectious diseases such as COVID‐19 is crucial for informed decision‐making and resource allocation. A critical component of disease behaviour is the velocity with which disease spreads, defined as the rate of change between time and space.
Fernando Rodriguez Avellaneda +2 more
wiley +1 more source
Ticks and Tick-Borne DiseasesTicks are important vectors of rickettsial pathogens, particularly in regions where livestock, wildlife, and humans overlap. Despite increasing reports of rickettsioses in India, molecular evidence of Rickettsia species in questing ticks from the Western
Vinayak V +8 more
doaj +1 more source
The Chikungunya Epidemic: A look at five cases
IDCases, 2015 Chikungunya is an infection caused by the Chikungunya virus and transmitted by the bite of infected mosquito. The most common symptoms of Chikungunya virus infection are fever, joint pain or rash.
Bethel Shiferaw +6 more
doaj +1 more source
The threat of Chikungunya in Oceania
Western Pacific Surveillance and Response Journal, 2013 [Extract] The Oceania region, which includes Australia, New Zealand, Papua New Guinea and the islands of the tropical Pacific Ocean, has historically been free from chikungunya. However, the 2011 outbreak in New Caledonia and the ongoing outbreak in Papua New Guinea have highlighted the risk to other communities in Oceania where there are competent ...
Horwood, Paul +5 more
openaire +6 more sources
Medical and Veterinary Entomology, EarlyView.The principal arboviral vector Aedes aegypti can develop in coastal brackish water field habitats (0.5–15 g/L salt) with larvae possessing thicker cuticles and greater resistance to the larvicide Temephos. Females emerging from brackish water‐developing preimaginal stages are now shown to have thicker and remodelled leg and abdominal cuticles and ...
Kokila Sivabalakrishnan +6 more
wiley +1 more source
Mouse Models of Chikungunya Virus
, 2016 The majority of medical advances have been made using animals. Studies using mouse models of chikungunya-induced disease have proven invaluable for dissecting the intricate nature of the immune response to this viral infection and identifying potential ...
Stefan Wolf +9 more
core +1 more source
Chikungunya Virus as the Agent of Emergent Viral Disease
Проблемы особо опасных инфекций, 2019 Chikungunya virus belongs to Alphavirus genus of the Togaviridae family. It is a member of Semliki Forest virus antigenic complex that includes antigenic related Semliki Forest, Chikungunya, O’ Nyong-nyong, Ross River viruses.
T. E. Sizikova +5 more
doaj +1 more source