Results 61 to 70 of about 55,640 (226)

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source

Estimating drivers of autochthonous transmission of Chikungunya virus in its invasion of the Americas

, 2015
Background: Chikungunya is an emerging arbovirus that has caused explosive outbreaks in Africa and Asia for decades and invaded the Americas just over a year ago.
Tatem, A.J., Andrew J. Tatem, Perkins, T. Alex, Metcalf, C.J.E., Bryan T. Grenfell, Tatem, Andrew J., C. Jessica E. Metcalf, Metcalf, C. Jessica E., Perkins, T.A., Grenfell, Bryan T., T. Alex Perkins, Grenfell, B.T.   +11 more
core   +1 more source

Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling [PDF]

, 2010
Chikungunya virus (CHIKV) is an emerging human pathogen transmitted by mosquitoes. Like that of other alphaviruses, CHIKV replication causes general host shutoff, leading to severe cytopathicity in mammalian cells, and inhibits the ability of infected ...
Ligtenberg, M., Suhrbier, A., Corinne Geertsema, Esther Schnettler, Fros, J., Just M. Vlak, Maarten Ligtenberg, Geertsema, C., Suhrbier, Andreas, Wen Jun Liu, Natalie A. Prow, Vlak, J.M., Dana L. Vanlandingham, Ligtenberg, Maarten, Khromykh, Alexander A., Jelke J. Fros, Vanlandingham, D.L., Vlak, Just M., Schnettler, E., Fros, J.J., Gorben P. Pijlman, Pijlman, G.P., Liu, W.J., Khromykh, A.A., Prow, A., Fros, Jelke J., Vanlandingham, Dana L., Liu, Wen Jun, Geertsema, Corinne, Prow, Natalie A., Alexander A. Khromykh, Schnettler, Esther, Pijlman, Gorben P., Andreas Suhrbier, Prow, N.A.   +34 more
core   +1 more source

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules

Immunity, Inflammation and Disease
Background Pattern recognition receptors (PRRs) are the receptors of the innate immune system that play a vital role in initiating innate immune response.
Meenal Sharma, Priyanka Wagh, Tanvi Shinde, Diptee Trimbake, Anuradha S. Tripathy   +4 more
doaj   +1 more source

Mosquito-Borne Viral Infections in the Krasnodar Territory ~ Risks of Autochthonous Cases of the Disease

Эпидемиология и вакцинопрофилактика, 2021
Introduction. Global climate changes affect the habitats of insects, including mosquitoes, which are carriers of dangerous natural focal infections. When mosquitos develop new territories, they create a potential threat to people who find themselves in ...
S. V. Lenshin, I. V. Patraman, S. V. Alkhovsky, O. I. Vyshemirsky   +3 more
doaj   +1 more source

Analysis of Gene Expression in Aedes aegypti Suggests Changes in Early Genetic Control of Mosquito Development

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
ABSTRACT Aedes aegypti, a critical vector for tropical diseases, poses significant challenges for studying its embryogenesis due to difficulties in removing its rigid chorion and achieving effective fixation for in situ hybridization. Here, we present novel methodologies for fixation, dechorionation, DAPI staining, and in situ hybridization, enabling ...
Renata Coutinho‐dos‐Santos, Danielle Santos, Lupis Ribeiro, Jonathan J. Mucherino‐Muñoz, Marcelle Uhl, Carlos Logullo, A. Mendonça‐Amarante, M. Fantappie, Rodrigo Nunes‐da‐Fonseca   +8 more
wiley   +1 more source

Knock‐knock, who is inside? Exploiting citizen science data to shed light on Aedes albopictus indoor presence in southern Europe

People and Nature, EarlyView.
Abstract Animal behaviour in human‐dominated landscapes is difficult to study at large spatial and temporal scales, especially for small species characterised by elusive movements. Citizen science can help overcome these limitations by turning routine human–animal encounters into observations of where and when species are active.
Eleonora Longo, Chiara Virgillito, Carlo Maria De Marco, Chiara Gentile, Martina Micocci, Paola Serini, Verena Pichler, Francesco Severini, Fabrizio Montarsi, Francesco Gradoni, Federico Filipponi, Frederic Bartumeus, John R. B. Palmer, Mattia Manica, Daniele Da Re, Roberto Rosà, Beniamino Caputo, Alessandra della Torre   +17 more
wiley   +1 more source

Automatic insect identification, counting, and monitoring techniques: a review

Pest Management Science, EarlyView.
Automated insect monitoring increasingly integrates optical, acoustic, infrared, radar, electrostatic, and biosensing technologies with artificial intelligence. No single approach is universally optimal; reliable deployment depends on task‐specific validation, representative datasets, robustness under field conditions, energy autonomy, connectivity ...
Mariano González García, Juan Carlos Noguera Polania, Rosana González Combarros, José Ignacio López Sánchez   +3 more
wiley   +1 more source

Illness in Children Presenting to the Emergency Department After International Travel: A 10‐Year Retrospective Analysis From the University Hospital of Helsinki, Finland

Acta Paediatrica, EarlyView.
ABSTRACT Aim We characterized infections after international travel and identified predictors of severe infection to refine management. Methods We conducted a retrospective cross‐sectional analysis of children aged 0–18 years presenting to Helsinki University Hospital Emergency Department within 90 days of international travel between January 1, 2015 ...
Tuula Pelkonen, Svetlana Vakkilainen
wiley   +1 more source

Chikungunya Masquerading as Acute Rheumatism in an Omani Traveler

Oman Medical Journal, 2019
Chikungunya is a mosquito-borne viral disease. It typically presents as an acute febrile illness associated with a varying degree of arthralgia and musculoskeletal sequelae.
Mohammed Al Amin, Shadin Ibrahim, Abdullah Balkhair, Ibrahim Al Busaidi, Zied Gaifer, Hashim Ba Taher   +5 more
doaj   +1 more source