Results 121 to 130 of about 1,757,770 (311)

FHL1 is a major host factor for chikungunya virus infection

Nature, 2019
Chikungunya virus (CHIKV) is a re-emerging alphavirus that is transmitted to humans by mosquito bites and causes musculoskeletal and joint pain1,2. Despite intensive investigations, the human cellular factors that are critical for CHIKV infection remain ...
L. Meertens, M. Hafirassou, T. Couderc, Lucie Bonnet-Madin, Vasiliya Kril, B. Kümmerer, Athéna Labeau, Alexis Brugier, Etienne Simon-Loriere, Julien Burlaud‐Gaillard, C. Doyen, L. Pezzi, Thibaud Goupil, Sophia Rafasse, P. Vidalain, Anne Bertrand-Legout, L. Gueneau, R. Juntas-Morales, R. Ben Yaou, G. Bonne, X. Lamballerie, M. Benkirane, P. Roingeard, C. Delaugerre, Marc Lecuit, A. Amara   +25 more
semanticscholar   +1 more source

Antivirals Against Chikungunya Virus: Is the Solution in Nature?

Viruses, 2020
The worldwide outbreaks of the chikungunya virus (CHIKV) in the last years demonstrated the need for studies to screen antivirals against CHIKV. The virus was first isolated in Tanzania in 1952 and was responsible for outbreaks in Africa and Southwest ...
Daniel Oliveira Silva Martins, Igor de Andrade Santos, Débora Moraes de Oliveira, Victória Riquena Grosche, Ana Carolina Gomes Jardim   +4 more
semanticscholar   +1 more source

Awareness towards Chikungunya virus infection risk by general practitioners in Rome: a questionnaire based survey before the 2017 outbreak [PDF]

, 2018
Autochthonous cases of Chikungunya (CHIKV) have been recently detected in Rome. A survey was conduct- ed prior to the 2017 outbreak to assess knowledge, attitude, and practices towards CHIKV infections on 103 randomly selected general practitioners (GPs),
Caputo, B., Di Lascio, A., Gatto, G., Russo, G., Solimini, A. G.   +4 more
core  

From eggs to bites: do ovitrap data provide reliable estimates of Aedes albopictus biting females? [PDF]

, 2017
Background. Aedes albopictus is an aggressive invasive mosquito species that represents a serious health concern not only in tropical areas, but also in temperate regions due to its role as vector of arboviruses.
Caputo, Beniamino, DELLA TORRE, Alessandra, Manica, Mattia, Rosà, Roberto   +3 more
core   +3 more sources

Universal Regulation of DNA Polymerase via Photocaged Primer Enables Light‐Start Isothermal Amplification on Demand

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing, Yufan Qin, Zhijin Li, Xiufang Yu, Jianbo Wang, Xiaoqiong Liu, Xin Chen, Chao Yu   +7 more
wiley   +1 more source

The neurological complications of chikungunya virus: A systematic review

Reviews in Medical Virology, 2018
We performed a systematic review on the neurological complications of chikungunya virus. Such complications are being reported increasingly, owing primarily to the scale of recent epidemics but also to a growing understanding of the virus' neurovirulence.
Ravi Mehta, P. Gérardin, C. A. A. de Brito, C. Soares, M. L. B. Ferreira, T. Solomon   +5 more
semanticscholar   +1 more source

Chikungunya Infection in Travelers

Emerging Infectious Diseases, 2006
The largest described outbreak of chikungunya virus has been occurring on the islands of the southwest Indian Ocean since March 2005. We describe the manifestations of chikungunya virus infection in travelers returning from these islands, with focus on ...
Patrick Hochedez, Stephane Jaureguiberry, Monique Debruyne, Philippe Bossi, Pierre Hausfater, Gilles Brucker, Francois Bricaire, Eric Caumes   +7 more
doaj   +1 more source

Determinants of the population growth of the West Nile virus mosquito vector Culex pipiens in a repeatedly affected area in Italy [PDF]

, 2014
Background The recent spread of West Nile Virus in temperate countries has raised concern. Predicting the likelihood of transmission is crucial to ascertain the threat to Public and Veterinary Health.
Bonfanti, L., Capelli, G., Ferguson, H.M., Marangon, S., Montarsi, F., Mulatti, P.   +5 more
core   +1 more source

Aptamer Engineering: Strategies for Discovering Functional Nucleic Acids for Next‐Generation Diagnostics and Biosensing

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The advent of aptamers has highlighted their potential as alternatives to antibodies, overcoming limitations of structural instability and production cost. However, conventional approaches such as SELEX remain slow and labor‐intensive. This review examines recent advances in aptamer engineering, emphasizing in vitro and AI‐driven in silico strategies ...
John V. L. Nguyen, Ahlem Meziadi, Cyrill Brunner, Maureen McKeague, Lidija Malic, Maryam Tabrizian   +5 more
wiley   +1 more source

Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

Science immunology, 2019
Anti–chikungunya virus antibodies require FcγR engagement but not complement activation for protection and viral clearance. Engaging monocytes to battle chikungunya Antibody-binding receptors, including Fc receptors and complement receptors, play a ...
J. Fox, Vicky Roy, B. Gunn, Ling Huang, M. Edeling, M. Mack, D. Fremont, B. Doranz, S. Johnson, G. Alter, M. Diamond   +10 more
semanticscholar   +1 more source