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Proteomic profiling of chikungunya virus-infected human muscle cells: Reveal the role of cytoskeleton network in CHIKV replication

Journal of Proteomics, 2014
Chikungunya virus (CHIKV) is an arthropod-borne, positive-sense, single-stranded RNA virus belonging to genus Alphavirus and family Togaviridae. The clinical manifestations developed upon CHIKV-infection include fever, myositis, arthralgia and maculopapular rash. Thus, the re-emergence of CHIKV has posed serious health threats worldwide.
Eng Lee Tan, Justin Jang Hann Chu
exaly   +3 more sources

Antibodies against chikungunya virus structural proteins reveal the presence of CHIKV virions in migrasomes

Journal of Immunological Methods
Chikungunya fever (CHIKF) is a viral illness transmitted by mosquitoes, caused by the chikungunya virus (CHIKV), which has led to millions of infections globally. Antibodies against CHIKV serve as essential tools for research on this virus. In this study, we designed peptides corresponding to the E1, E2, E3, and capsid proteins of CHIKV to immunize New
Leiliang Zhang
exaly   +3 more sources

Chikungunya virus nsP3 & nsP4 interacts with HSP-90 to promote virus replication: HSP-90 inhibitors reduce CHIKV infection and inflammation in vivo

Antiviral Research, 2014
The global emergence of Chikungunya virus (CHIKV) infection is alarming and currently there is no licensed vaccine or antiviral treatment available to mitigate this disease. CHIKV infection typically results in high viral load with an outcome of high fever, skin rashes, muscle pain, and sequelae of prolonged arthritis, which occurs in >90% of the ...
Abhay P S Rathore   +2 more
exaly   +3 more sources

Chikungunya Virus (Chikv): General Characteristics and Possible Impact on Hemotherapy

La Prensa Medica, 2015
Chikungunya Virus (Chikv): General Characteristics and Possible Impact on Hemotherapy Chikungunya virus (CHIKV) is an arbovirus belonging to the Alphavirus genus of the Togaviridae family. The virus is transmitted by Aedes mosquitos, the most important of which are A. aegypti and A. albopictus.
Svetoslav Nanev Slavov   +1 more
openaire   +1 more source

Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004

The American Journal of Tropical Medicine and Hygiene, 2008
An outbreak of Chikungunya virus (CHIKV) disease associated with high fever and severe protracted arthralgias was detected in Lamu, Kenya, peaking in July 2004. At least 1,300 cases were documented. We conducted a seroprevalence study to define the magnitude of transmission on Lamu Island. We conducted a systematic cross-sectional survey.
Kibet, Sergon   +12 more
openaire   +2 more sources

Chikungunya Virus (CHIKV): Coming to America

Biosafety, 2014
Chikungunya Virus (CHIKV) is an arbovirus of the alphavirus genus (Togaviridae family) transmitted by the bite of infected Aedes mosquitoes. The word, Chikungunya, translates to “that which bends up”, based on the stooped position of patients during the rheumatic symptoms of the disease.
openaire   +1 more source

Magnetic Resonance Imaging Brain Findings in Chikungunya Virus (CHIKV) Infection with Neurological Complication during Epidemic Outbreak

Neurology India, 2023
Background and Objective: The Chikungunya virus is an alphavirus RNA of the family Togaviridae transmitted by the Aedes mosquito. We aim to report magnetic resonance imaging (MRI) brain findings for neurological complications at our institute during epidemic outbreak. Materials and Methods:
Kanika Sekhri, Sethi   +2 more
openaire   +2 more sources

A Child with Serious Chikungunya Virus (CHIKV) Infection Requiring Intensive Care, After an Outbreak

The Indian Journal of Pediatrics, 2010
A 5 1/2-yr-old boy presented with high grade fever for 4 days, and cervical adenitis, body ache, arthralgia, followed by sudden onset of breathlessness. He had clinical, electrocardiographic and echo evidence of myocarditis and congestive cardiac failure.
P Ramesh, Menon   +4 more
openaire   +2 more sources

Nanotechnology: A promising approach of antiviral treatments against chikungunya virus (CHIKV)

Journal of Scientific and Innovative Research, 2018
Following its emergence in Africa, spread to the Indian Ocean islands in 2006, and occurrences in regions of the world where it hadn’t been reported in the past, Chikungunya has become an emerging public health concern in many countries. The past outbreaks of the chikungunya virus (CHIKV) have caused widespread morbidity and mortality.
Rishikesh Kumar   +9 more
openaire   +1 more source

Chikungunya Virus (CHIKV): The Novel Challenge to the Healthcare System

Pakistan Journal of Medical & Health Sciences
Chikungunya (CHIKV) is a viral illness transmitted by mosquitoes, characterized by fever and intense arthralgia. It is induced by a ribonucleic acid (RNA) virus classified within the alphavirus genus of the Togaviridae family1. The word “chikungunya” originates from a phrase in the Kimakonde phrases of southern the Republic of Tanzania, indicating “to ...
Pir eh   +5 more
openaire   +1 more source

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