Results 181 to 190 of about 1,052,896 (217)

Antibodies against chikungunya virus structural proteins reveal the presence of CHIKV virions in migrasomes

Journal of Immunological Methods
Chikungunya fever (CHIKF) is a viral illness transmitted by mosquitoes, caused by the chikungunya virus (CHIKV), which has led to millions of infections globally. Antibodies against CHIKV serve as essential tools for research on this virus. In this study, we designed peptides corresponding to the E1, E2, E3, and capsid proteins of CHIKV to immunize New
Leiliang Zhang
exaly   +3 more sources

Proteomic profiling of chikungunya virus-infected human muscle cells: Reveal the role of cytoskeleton network in CHIKV replication

Journal of Proteomics, 2014
Chikungunya virus (CHIKV) is an arthropod-borne, positive-sense, single-stranded RNA virus belonging to genus Alphavirus and family Togaviridae. The clinical manifestations developed upon CHIKV-infection include fever, myositis, arthralgia and maculopapular rash. Thus, the re-emergence of CHIKV has posed serious health threats worldwide.
Justin Jang Hann Chu, Eng Lee Tan
exaly   +3 more sources

A recombinant CHIKV-NLuc virus identifies chondrocytes as target of Chikungunya virus in a immunocompetent mouse model

Abstract First isolated in 1953 in Tanzania, the arthritogenic Chikungunya virus (CHIKV) re-emerged globally in 2005, leading to widespread outbreaks. Unlike other arboviruses, CHIKV predominantly induces symptomatic infections (72-96%), marked by fever, myalgia, polyarthralgia, and rash.
Legros, Vincent, Belarbi, Essia, Jeannin, Patricia, Kümmerer, Beate, Hardy, David, Desprès, Philippe, Gessain, Antoine, Roques, Pierre, Ceccaldi, Pierre-Emmanuel, Choumet, Valérie   +9 more
openaire   +2 more sources

A booster regime of liposome-delivered live-attenuated CHIKV vaccine RNA genome protects against chikungunya virus disease in mice

Vaccine, 2023
Mosquito-transmitted chikungunya virus (CHIKV) is the causal pathogen of CHIKV disease and is responsible for global epidemics of arthritic disease. CHIKV infection can lead to severe chronic and debilitating arthralgia, significantly impacting patient ...
Abeyratne, E, Yang, C, Liu, X, Shambhavi Rao, Ali Zaid, Helen Mostafavi, Zaid, A, Rao, S, Freitas, JR, Tharmarajah, K, Kothila Tharmarajah, Adam Taylor, Mehfuz Zaman, Xiang Liu, Mostafavi, H, Suresh Mahalingam, Zaman, M, Joseph R. Freitas, Eranga Abeyratne, Mahalingam, S, Chenying Yang, Taylor, A   +21 more
exaly   +2 more sources

Chikungunya Virus (Chikv): General Characteristics and Possible Impact on Hemotherapy

La Prensa Medica, 2015
Chikungunya Virus (Chikv): General Characteristics and Possible Impact on Hemotherapy Chikungunya virus (CHIKV) is an arbovirus belonging to the Alphavirus genus of the Togaviridae family. The virus is transmitted by Aedes mosquitos, the most important of which are A. aegypti and A. albopictus.
Svetoslav Nanev Slavov, Katia Kaori Otaguiri   +1 more
openaire   +1 more source

Chikungunya Virus (CHIKV): Coming to America

Biosafety, 2014
Chikungunya Virus (CHIKV) is an arbovirus of the alphavirus genus (Togaviridae family) transmitted by the bite of infected Aedes mosquitoes. The word, Chikungunya, translates to “that which bends up”, based on the stooped position of patients during the rheumatic symptoms of the disease.
openaire   +1 more source

Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004

The American Journal of Tropical Medicine and Hygiene, 2008
An outbreak of Chikungunya virus (CHIKV) disease associated with high fever and severe protracted arthralgias was detected in Lamu, Kenya, peaking in July 2004. At least 1,300 cases were documented. We conducted a seroprevalence study to define the magnitude of transmission on Lamu Island. We conducted a systematic cross-sectional survey.
Kibet, Sergon, Charles, Njuguna, Rosalia, Kalani, Victor, Ofula, Clayton, Onyango, Limbaso S, Konongoi, Sheryl, Bedno, Heather, Burke, Athman M, Dumilla, Joseph, Konde, M Kariuki, Njenga, Rosemary, Sang, Robert F, Breiman   +12 more
openaire   +2 more sources

A Child with Serious Chikungunya Virus (CHIKV) Infection Requiring Intensive Care, After an Outbreak

The Indian Journal of Pediatrics, 2010
A 5 1/2-yr-old boy presented with high grade fever for 4 days, and cervical adenitis, body ache, arthralgia, followed by sudden onset of breathlessness. He had clinical, electrocardiographic and echo evidence of myocarditis and congestive cardiac failure.
P Ramesh, Menon, Krishnan, C, Jayaram, Sankar, K M, Gopinathan, Girija, Mohan   +4 more
openaire   +2 more sources

Chikungunya Virus (CHIKV): The Novel Challenge to the Healthcare System

Pakistan Journal of Medical & Health Sciences
Chikungunya (CHIKV) is a viral illness transmitted by mosquitoes, characterized by fever and intense arthralgia. It is induced by a ribonucleic acid (RNA) virus classified within the alphavirus genus of the Togaviridae family1. The word “chikungunya” originates from a phrase in the Kimakonde phrases of southern the Republic of Tanzania, indicating “to ...
Pir eh, Iffat Jamal, Syed Zulfiqar Ali Shah, Muqadas Fatima, Farheen Qadeer, Mushahid Ali   +5 more
openaire   +1 more source