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A Booster Regime of Liposome-Delivered Live-Attenuated CHIKV Vaccine RNA Genome Protects Against Chikungunya Virus Disease in Mice [PDF]

Vaccine, 2023
Mosquito-transmitted chikungunya virus (CHIKV) is the causal pathogen of CHIKV disease and is responsible for global epidemics of arthritic disease. CHIKV infection can lead to severe chronic and debilitating arthralgia, significantly impacting patient ...
Kothila Tharmarajah, Eranga Abeyratne
exaly   +2 more sources

Extensive Evolution Analysis of the Global Chikungunya Virus Strains Revealed the Origination of CHIKV Epidemics in Pakistan in 2016 [PDF]

Virologica Sinica, 2017
Chikungunya virus (CHIKV) is a mosquito-borne virus that causes epidemics widely in the world especially in the tropical and subtropical regions. Phylogenetic analysis has found that the CHIKV lineages were associated with the spatial and temporal distributions, which were related to the virus adaption to the major mosquito species and their ...
Shu Shen, Fei Deng, Bo Zhang
exaly   +3 more sources

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Chikungunya Virus (Chikv): General Characteristics and Possible Impact on Hemotherapy

La Prensa Medica, 2015
Chikungunya Virus (Chikv): General Characteristics and Possible Impact on Hemotherapy Chikungunya virus (CHIKV) is an arbovirus belonging to the Alphavirus genus of the Togaviridae family. The virus is transmitted by Aedes mosquitos, the most important of which are A. aegypti and A. albopictus.
Svetoslav Nanev Slavov, Katia Kaori Otaguiri   +1 more
openaire   +1 more source

Chikungunya Virus (CHIKV): Coming to America

Biosafety, 2014
Chikungunya Virus (CHIKV) is an arbovirus of the alphavirus genus (Togaviridae family) transmitted by the bite of infected Aedes mosquitoes. The word, Chikungunya, translates to “that which bends up”, based on the stooped position of patients during the rheumatic symptoms of the disease.
openaire   +1 more source

Seroprevalence of Chikungunya Virus (CHIKV) Infection on Lamu Island, Kenya, October 2004

The American Journal of Tropical Medicine and Hygiene, 2008
An outbreak of Chikungunya virus (CHIKV) disease associated with high fever and severe protracted arthralgias was detected in Lamu, Kenya, peaking in July 2004. At least 1,300 cases were documented. We conducted a seroprevalence study to define the magnitude of transmission on Lamu Island. We conducted a systematic cross-sectional survey.
Kibet, Sergon, Charles, Njuguna, Rosalia, Kalani, Victor, Ofula, Clayton, Onyango, Limbaso S, Konongoi, Sheryl, Bedno, Heather, Burke, Athman M, Dumilla, Joseph, Konde, M Kariuki, Njenga, Rosemary, Sang, Robert F, Breiman   +12 more
openaire   +2 more sources

A Child with Serious Chikungunya Virus (CHIKV) Infection Requiring Intensive Care, After an Outbreak

The Indian Journal of Pediatrics, 2010
A 5 1/2-yr-old boy presented with high grade fever for 4 days, and cervical adenitis, body ache, arthralgia, followed by sudden onset of breathlessness. He had clinical, electrocardiographic and echo evidence of myocarditis and congestive cardiac failure.
P Ramesh, Menon, Krishnan, C, Jayaram, Sankar, K M, Gopinathan, Girija, Mohan   +4 more
openaire   +2 more sources

Chikungunya Virus (CHIKV): The Novel Challenge to the Healthcare System

Pakistan Journal of Medical & Health Sciences
Chikungunya (CHIKV) is a viral illness transmitted by mosquitoes, characterized by fever and intense arthralgia. It is induced by a ribonucleic acid (RNA) virus classified within the alphavirus genus of the Togaviridae family1. The word “chikungunya” originates from a phrase in the Kimakonde phrases of southern the Republic of Tanzania, indicating “to ...
Pir eh, Iffat Jamal, Syed Zulfiqar Ali Shah, Muqadas Fatima, Farheen Qadeer, Mushahid Ali   +5 more
openaire   +1 more source

Nanotechnology: A promising approach of antiviral treatments against chikungunya virus (CHIKV)

Journal of Scientific and Innovative Research, 2018
Following its emergence in Africa, spread to the Indian Ocean islands in 2006, and occurrences in regions of the world where it hadn’t been reported in the past, Chikungunya has become an emerging public health concern in many countries. The past outbreaks of the chikungunya virus (CHIKV) have caused widespread morbidity and mortality.
Rishikesh Kumar, Ganesh C Sahoo, null Bhawna, Aparna Ramachandran, Md. Yousuf Ansari, Krishna Pandey, VNR Das, RK Topno, Major Madhukar, Pradeep Das   +9 more
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Magnetic Resonance Imaging Brain Findings in Chikungunya Virus (CHIKV) Infection with Neurological Complication during Epidemic Outbreak

Neurology India, 2023
Background and Objective: The Chikungunya virus is an alphavirus RNA of the family Togaviridae transmitted by the Aedes mosquito. We aim to report magnetic resonance imaging (MRI) brain findings for neurological complications at our institute during epidemic outbreak.
Kanika Sekhri, Sethi, Abhay Kumar, Aryan, Prem Kumar, Ganeshan   +2 more
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Antibodies Against Chikungunya Virus Structural Proteins Reveal the Presence of CHIKV Virions in Migrasomes

Journal of Immunological Methods
Chikungunya fever (CHIKF) is a viral illness transmitted by mosquitoes, caused by the chikungunya virus (CHIKV), which has led to millions of infections globally. Antibodies against CHIKV serve as essential tools for research on this virus. In this study, we designed peptides corresponding to the E1, E2, E3, and capsid proteins of CHIKV to immunize New
Leiliang Zhang, Xichi Tang, Haiyan Huang
exaly   +3 more sources