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Chikungunya Virus (CHIKV): The Novel Challenge to the Healthcare System

Pakistan Journal of Medical & Health Sciences
Chikungunya (CHIKV) is a viral illness transmitted by mosquitoes, characterized by fever and intense arthralgia. It is induced by a ribonucleic acid (RNA) virus classified within the alphavirus genus of the Togaviridae family1. The word “chikungunya” originates from a phrase in the Kimakonde phrases of southern the Republic of Tanzania, indicating “to ...
Pir eh   +5 more
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Antibodies against chikungunya virus structural proteins reveal the presence of CHIKV virions in migrasomes

Journal of Immunological Methods
Chikungunya fever (CHIKF) is a viral illness transmitted by mosquitoes, caused by the chikungunya virus (CHIKV), which has led to millions of infections globally. Antibodies against CHIKV serve as essential tools for research on this virus. In this study, we designed peptides corresponding to the E1, E2, E3, and capsid proteins of CHIKV to immunize New
Shengnan, Wang   +4 more
openaire   +2 more sources

Proteomic profiling of chikungunya virus-infected human muscle cells: Reveal the role of cytoskeleton network in CHIKV replication

Journal of Proteomics, 2014
Chikungunya virus (CHIKV) is an arthropod-borne, positive-sense, single-stranded RNA virus belonging to genus Alphavirus and family Togaviridae. The clinical manifestations developed upon CHIKV-infection include fever, myositis, arthralgia and maculopapular rash. Thus, the re-emergence of CHIKV has posed serious health threats worldwide.
Too Horng Khit, Issac   +2 more
openaire   +2 more sources

Diagnosing the Outbreak and Spread of the Chikungunya Virus in Central & South America - The DARPA CHIKV Challenge

Journal of Clinical and Biomedical Advances, 2023
In 2014, the U.S. Defense Advanced Research Projects Agency (DARPA) issued a “challenge” to forecast the future outbreaks and spreads of the virus Chikungunya Virus (CHIKV) in Central and South America. We took on the challenge of predicting the cumulative number of Pacific Atlantic Health Organization (PAHO) reported Chikungunya or CHIKV cases by ...
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Chikungunya virus (CHIKV): What can be expected after the acute phase?

Reumatología Clínica (English Edition), 2016
Vianna J, Khoury, Pablo R, Camilo
openaire   +2 more sources

A recombinant CHIKV-NLuc virus identifies chondrocytes as target of Chikungunya virus in a immunocompetent mouse model

AbstractFirst isolated in 1953 in Tanzania, the arthritogenic Chikungunya virus (CHIKV) re-emerged globally in 2005, leading to widespread outbreaks. Unlike other arboviruses, CHIKV predominantly induces symptomatic infections (72-96%), marked by fever, myalgia, polyarthralgia, and rash.
Vincent Legros   +9 more
openaire   +1 more source

EPH160 Burden of Illness (BOI) and Paucity of Treatment of the Mosquito-Borne Chikungunya Virus (CHIKV)

Value in Health, 2022
K Bakker   +4 more
openaire   +1 more source

Biology and pathogenesis of chikungunya virus

Nature Reviews Microbiology, 2010
Olivier Schwartz, Matthew L Albert
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