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Proteomic Profiling of Chikungunya Virus-Infected Human Muscle Cells: Reveal the Role of Cytoskeleton Network in CHIKV Replication

Journal of Proteomics, 2014
Chikungunya virus (CHIKV) is an arthropod-borne, positive-sense, single-stranded RNA virus belonging to genus Alphavirus and family Togaviridae. The clinical manifestations developed upon CHIKV-infection include fever, myositis, arthralgia and maculopapular rash. Thus, the re-emergence of CHIKV has posed serious health threats worldwide.
Justin Jang Hann Chu, Eng Lee Tan
exaly   +3 more sources

Diagnosing the Outbreak and Spread of the Chikungunya Virus in Central & South America - The DARPA CHIKV Challenge

Journal of Clinical and Biomedical Advances, 2023
In 2014, the U.S. Defense Advanced Research Projects Agency (DARPA) issued a “challenge” to forecast the future outbreaks and spreads of the virus Chikungunya Virus (CHIKV) in Central and South America. We took on the challenge of predicting the cumulative number of Pacific Atlantic Health Organization (PAHO) reported Chikungunya or CHIKV cases by ...
openaire   +1 more source

Chikungunya Virus (CHIKV) Pathogenesis: From Acute Fever to Chronic Arthritis—Immune Mechanisms and Therapeutic Implications

Current Topics in Medicinal Chemistry
Chikungunya Virus (CHIKV) is an arthropod-borne alphavirus that represents a substantial worldwide health burden. A percentage of patients go on to suffer from Chronic Chikungunya Arthritis (CCA) that lasts for months, or even years, and causes disability.
Dongbing Li, Guizhen Lyu
openaire   +2 more sources

A recombinant CHIKV-NLuc virus identifies chondrocytes as target of Chikungunya virus in a immunocompetent mouse model

Abstract First isolated in 1953 in Tanzania, the arthritogenic Chikungunya virus (CHIKV) re-emerged globally in 2005, leading to widespread outbreaks. Unlike other arboviruses, CHIKV predominantly induces symptomatic infections (72-96%), marked by fever, myalgia, polyarthralgia, and rash.
Legros, Vincent   +9 more
openaire   +1 more source

Chikungunya virus (CHIKV): What can be expected after the acute phase?

Reumatología Clínica (English Edition), 2016
Vianna J, Khoury, Pablo R, Camilo
openaire   +2 more sources

EPH160 Burden of Illness (BOI) and Paucity of Treatment of the Mosquito-Borne Chikungunya Virus (CHIKV)

Value in Health, 2022
K Bakker   +4 more
openaire   +1 more source

Biology and Pathogenesis of Chikungunya Virus

Nature Reviews Microbiology, 2010
Matthew L Albert, Olivier Schwartz
exaly  

Development of a Specific CHIKV-E2 Monoclonal Antibody for Chikungunya Diagnosis

Virologica Sinica, 2019
Jihyun Yang   +2 more
exaly  

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