Results 201 to 210 of about 15,961 (231)

Identification of CHIKV biomarkers in serum of CHIKV-infected mice and a high affinity ssDNA aptamer against E2 as bioreceptor for diagnosis.

2021
Chikungunya virus (CHIKV) which is mosquito-borne, causes fever and joint pain in human. Diagnosis of CHIKV infection is via laboratory detection of viral genes and antibodies requiring specialized instruments and technical skills, which are unsuitable for point-of-care diagnosis.
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Proteomic analysis of CHIKV‐infected human fibroblast‐like synoviocytes: Identification of host factors potentially associated with CHIKV replication and cellular pathogenesis

Microbiology and Immunology, 2020
AbstractChikungunya virus (CHIKV) is a mosquito‐borne virus that causes arthralgic fever. Fibroblast‐like synoviocytes play a key role in joint damage in inflammatory arthritides and can additionally serve as target cells for CHIKV infection. To gain a better understanding of CHIKV‐induced arthralgia, the interaction between CHIKV and synoviocytes was ...
Apamas Sukkaew, Ampa Suksatu, Sittiruk Roytrakul, Duncan R. Smith, Sukathida Ubol   +4 more
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Role of Proinflammatory Cytokines and Chemokines in Chronic Arthropathy in CHIKV Infection

Viral Immunology, 2011
Chikungunya virus (CHIKV) has caused large outbreaks worldwide in recent years. Acute-phase CHIKV infection has been reported to cause mild to severe febrile illness, and in some patients, this may be followed by long-lasting polyarthritis. The mainstay of treatment includes nonsteroidal anti-inflammatory drugs and other disease-modifying agents, the ...
Itta Krishna, Chaaitanya, Nagarajan, Muruganandam, Senthil G, Sundaram, Omkar, Kawalekar, Attayur P, Sugunan, Sathya P, Manimunda, Sruti R, Ghosal, Karuppiah, Muthumani, Paluru, Vijayachari   +8 more
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Genomic Epidemiology of CHIKV During the Largest Outbreak in Mainland China-Implication for CHIKV intervention

Abstract Chikungunya virus (CHIKV) has caused recurrent epidemics across tropical and subtropical regions globally. In 2025, Guangdong, China, experienced the largest documented CHIKV outbreak in mainland China, with 23,464 reported cases across all 21 prefecture-level cities.
Lina Yi, Silin Xiang, Xuhe Huang, Jianhua Huang, Mingji Chen, Heshi Long, Yuwei He, Chuting Zeng, Guanghu Zhu, Shuyan Tan, Xiaofang Peng, Zhe Liu, Shanshan Gao, Jing Lu   +13 more
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Stability of delayed CHIKV dynamics model with cell-to-cell transmission

Journal of Intelligent & Fuzzy Systems, 2019
This paper investigates the global dynamics of Chikungunya virus (CHIKV) infection model with antibody immune response. We incorporate two ways of transmissions CHIKV-to-cell and cell-to-cell. We incorporate three types of discrete time delays into the model.
Ahmed M. Elaiw, Sami E. Almalki, Aatef D. Hobiny   +2 more
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Global dynamics of delayed CHIKV infection model with multitarget cells

Journal of Applied Mathematics and Computing, 2018
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Ahmed M. Elaiw, Taofeek O. Alade, Saud M. Alsulami   +2 more
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CHIKV in humanized mice

Lab Animal, 2021
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INTELLIGENT TOPOLOGY BASED DECISION MAKING IN CHIKV

This paper's goal is to provide a novel topology known as rough topology in terms of rough sets and demonstrate how rough topology may be applied to the analysis of several real-world and practical issues. This idea is used to determine the determining characteristics for the most prevalent CHIKV diseases.
G. Ranjani, D. Nagarajan, K. Jayalakshmii, T. S. Thilagavathi   +3 more
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Analysis of CHIKV in Mosquitoes Infected via Artificial Blood Meal

2016
Having a mechanism to assess the transmission dynamics of a vector-borne virus is one critical component of understanding the life cycle of these viruses. Laboratory infection systems using artificial blood meals is one valuable approach for monitoring the progress of virus in its mosquito host and evaluating potential points for interruption of the ...
Jeremy P, Ledermann, Ann M, Powers
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Promising inhibitors of nsp2 of CHIKV using molecular docking and temperature-dependent molecular dynamics simulations

Journal of Biomolecular Structure and Dynamics, 2022
Indra Bahadur, Prashant Singh, Nagendra K Kaushik   +2 more
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