Results 81 to 90 of about 15,961 (231)
An international study on emerging arboviral infections and blood safety
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra +40 more
wiley +1 more source
Validation of the CHIKV high-throughput assay.
Scatter plot and calculated Z'-factor of the resazurin reduction assay for CHIKV high-throughput screening. Dots represent wells with the following treatment: MOCK-infected HuH-7 (blue), CHIKV-infected HuH-7 with 0.5% DMSO vehicle (red), and 5 µM MPA ...
Benoit Lombardot (478538) +9 more
core +1 more source
Influence of Heat Wave and Precipitation on Chikungunya Transmission
Abstract Increasingly frequent extreme weather events are heightening the chances of mosquito‐borne diseases outbreaks, posing a notable threat to human health. However, how extreme weather influences the transmission dynamics of mosquito‐borne diseases remains poorly understood.
Wei Yan +4 more
wiley +1 more source
Evaluation of medicinal herbs for Anti-CHIKV activity.
Chikungunya, a mosquito-borne viral disease is now a global public health problem. In tropical countries such as India, periodic chikungunya outbreaks can occur due the high prevalence of the mosquito vector, circulation of virus and the high population density.
Siva, Raghavendhar +3 more
openaire +2 more sources
Treatment of Chikungunya Virus (CHIKV) Using Targeted Immunotherapy
Chikungunya virus (CHIKV) is the most common mosquito-borne Alphavirus infecting humans worldwide. Up to date, there are no antiviral treatments or vaccines approved to treat or prevent CHIKV for which treatments remain symptomatic based on clinical manifestations.
Fleury Augustin Nsole Biteghe +5 more
openaire +2 more sources
Mosquito cell-specific glycosylation reduces CHIKV infectivity.
(A) SDS-PAGE image for CHIKVvero and CHIKVmos proteins that were treated with PNGase F to remove N-glycans from viral glycoproteins. (B-E) Vero cells or C6/36 cells were infected for 20 h with parental stocks of CHIKV (Ross) in the presence of ...
Dhiraj Acharya (815914) +4 more
core +1 more source
ABSTRACT In 2023 and 2024, Espírito Santo state, Brazil, experienced its largest dengue epidemic in 30 years, with record numbers of cases and deaths. This study aimed to characterize confirmed dengue cases and the dengue virus (DENV) during the epidemic and pre‐epidemic periods.
Nicolli Ribeiro de Jesus +18 more
wiley +1 more source
Targeting functional RNA structures in CHIKV and ZIKV
Emerging arboviruses such as Zika virus (ZIKV) and Chikungunya virus (CHIKV) represent a significant threat to human health and have a high potential to cause outbreaks in the near future. At present, there are no specific antivirals available for either of these important pathogens, despite the wide global prevalence of their vector, Aedes spp ...
Oliver Prosser +3 more
openaire +1 more source
Relationship between symptomatic CHIKV infection and baseline enrollment CHIKV PRNT status.a
aBased on 853 subjects with both enrollment and 12-month blood collections.bCHIKV PRNT titer at enrollment using 80% plaque reduction of attenuated vaccine strain 181/clone25.CHIKV = chikungunya virus; PRNT = plaque reduction neutralization test; n ...
Chonticha Klungthong (287990) +15 more
core +1 more source
Dengue (DENV) and Chikungunya (CHIKV) viruses can be transmitted simultaneously by Aedes mosquitoes, and there may be co-infections in humans. However, how the adaptive immune response is modified in the host has yet to be known entirely.
Araceli Posadas-Mondragón +9 more
doaj +1 more source

