Results 61 to 70 of about 7,593,002 (356)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Child Labour Stories [PDF]

, 2005
Three stories of child labor presented by the International Labour Organization (ILO)
International Labour Organization
core   +1 more source

Social workers’ views about children’s and parents’ competence in child protection decision-making [PDF]

, 2020
Johanna Korpinen, Tarja Pösö
openalex   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Peckham Street Training [PDF]

, 2008
Peckham Street Training is a new collaboration between artist Lottie Child and net-art organisation Furtherfield.org. Peckham Street Training tours introduced new ways of reclaiming public space.
Child, Lottie
core  

The influence of mothers' and fathers' parenting stress and depressive symptoms on own and partner's parent-child communication [PDF]

, 2013
This study examines how parenting stress and depressive symptoms experienced by mothers and fathers influence their own (actor effects) and the partner's (partner effects) parent–child communication. Based on the Actor-Partner Interdependence Model, data
Abidin, Abidin, Ackard, Almeida, American Psychiatric Association, Baril, Barnes, Beardslee, Belsky, Belsky, Bronte-Tinkew, Cabrera, Cooper, Cox, Crnic, Crnic, Cummings, Cummings, Davies, Deater-Deckard, Deater-Deckard, Dorn, Elgar, Erel, Fergusson, Gazendam-Donofrio, Gerris, Gerris, Goodman, Goodman, Goodman, Huizinga, Jackson, Jacob, Kenny, Kenny, Lamb, Ledermann, Lovejoy, Malmberg, McLeod, Middleton, Minuchin, Mitchell, Muthén, Nelson, Phares, Phares, Podsakoff, Radloff, Riesch, Schacht, Seginer, Semmer, Van de Velde, Van den Troost, Wilson   +56 more
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Neosporosis in 21 adult dogs, 2010‐2023

Journal of Veterinary Internal Medicine
Background Limited information is available regarding the clinical features, treatment, and prognosis of neosporosis in adult dogs. Objective Describe the clinical signs, laboratory findings, magnetic resonance imaging (MRI) findings, treatment and ...
Alexandra Kennedy, Joanna D. White, Georgina Child   +2 more
doaj   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source