Results 81 to 90 of about 5,994,958 (304)
The influence of biological sex and sex hormones on bile acid synthesis and cholesterol homeostasis
Biology of Sex Differences, 2019 Obesity and elevated serum lipids are associated with a threefold increase in the risk of developing atherosclerosis, a condition that underlies stroke, myocardial infarction, and sudden cardiac death.
Taylor Phelps +4 more
doaj +1 more source
Engaging marginalised and vulnerable families [PDF]
This Policy Brief explores the evidence regarding improving access to services for marginalised and vulnerable families with young children, and how families can best be engaged and supported. Why is this issue important?
Centre for Community Child Health
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, 1994 Biblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 planta; 28014 Madrid; Tel.
openaire +2 more sources
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
This paper compares and contrasts Tokyo's innovation structure with the industrial districts model and the international hub model in the literature on urban and regional development.
Child Hill, Richard, Fujita, Kumiko
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Summary of Findings from the Child Labor Surveys in the Cocoa Sector of West Africa [PDF]
, 2002 International Child Labor Program - Bureau of International Affairs (ILAB)ChildLaborCocoaFindings.pdf: 1028 downloads, before Oct.
International Child Labor Program, U.S.
core +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Childhood mental health: promotion, prevention and early intervention [PDF]
Good mental health is essential for children\u27s learning, social development, self-esteem and resilience to stress throughout the life-course. Over half a million Australian children have significant mental health problems.
Centre for Community Child Health
core
Learning to Act with RVRL Agents [PDF]
, 2007 The use of reinforcement learning to guide action selection of cognitive agents has been shown to be a powerful technique for stochastic environments. Standard Reinforcement learning techniques used to provide decision theoretic policies rely, however ...
Child, C. H. T., Garcez, A., Stathis, K.
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