Results 71 to 80 of about 975,826 (313)
Children's Human Capabilities and Child Maltreatment
Journal de Ciencias Sociales, 2020 There are no known studies that have explored a conceptual basis for valorizing child maltreatment as a human development impediment using the Human Capability Approach.
Clementia Eugene, Tobi L. G. Graafsma
doaj +1 more source
Advanced Science, EarlyView.In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi +10 more
wiley +1 more source
Safeguarding children and young people from sexual exploitation (consultation document) [PDF]
, 2010 "This guidance is designed to assist practitioners in preventing child sexual exploitation (CSE), protecting children and young people who are at risk of abuse or are abused through sexual exploitation, and disrupting and prosecuting those who perpetrate
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Advanced Science, EarlyView.Upon ischemia/reperfusion‐induced iron overload condition, neurons and astrocytes exhibit similar oxidative stress changes but opposite alterations in endogenous antioxidant defense mechanisms, leading to divergent ferroptotic outcomes. The iron deposition and neuronal loss are increased within the perilesional cortex of stroke patients ...
Yi Guo +17 more
wiley +1 more source
A critical review of child abuse and its management in Africa
African Journal of Emergency Medicine, 2017 Introduction: Child abuse in Africa is a major threat to the achievement of the sustainable development goals on the continent and has become increasingly topical with a dramatic increase in recognition and an appreciation of the long term harmful ...
Eben Badoe
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Child Abuse Programme Guiding Principles: Background and a More Detailed Elaboration of the Programmatic Implications of the Guiding Principles [PDF]
, 2012 Oak Foundation's Child Abuse Programme puts the child at the centre of all the work it supports. This statement has guided the foundation's work over the past decade, and we now feel that it is time to clarify and expand on this, with some additional ...
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Advanced Science, EarlyView.Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan +6 more
wiley +1 more source
Child Sexual Abuse and Exploitation: Guest Editor’s Introduction
International Journal for Crime, Justice and Social Democracy, 2015 One of the most unnerving aspects of child sexual abuse is that it is constantly manifesting in unexpected ways. The current Royal Commission into Institutional Responses to Child Sexual Abuse has collected testimony of abuse in churches, schools, out-of-
Michael Salter
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Advanced Science, EarlyView.A programmable 3D Neuron‐Injury‐on‐a‐Chip platform integrates multiaxial mechanical loading with ultrasensitive electrochemical biosensing to decode neuronal responses in real time. By mimicking physiologically relevant extension–torsion forces, the system reveals load‐specific biomarker trajectories (T‐Tau, NFL), gene regulation, and apoptosis.
Sultan Khetani +12 more
wiley +1 more source