Results 81 to 90 of about 211,434 (317)

CD177 Deficiency Defines a Stable Subtype of Human Neutrophil Granulocytes with Tumor Promoting Activity

open access: yesAdvanced Science, EarlyView.
Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung   +39 more
wiley   +1 more source

Transcript of Commission to Eliminate Child Abuse and Neglect Fatalities Hearing: December 7-8 , 2015 [PDF]

open access: yes, 2015
Transcript of a public hearing held by the Commission to Eliminate Child Abuse and Neglect Fatalities (CECANF) held December 7-8, 2015 in Herndon, Virginia.
CQ Transcriptions
core  

Children's Human Capabilities and Child Maltreatment

open access: yesJournal de Ciencias Sociales, 2020
There are no known studies that have explored a conceptual basis for valorizing child maltreatment as a human development impediment using the Human Capability Approach.
Clementia Eugene, Tobi L. G. Graafsma
doaj   +1 more source

Fatty Acid Binding Protein 5 Mediates Astrocytic Pyroptosis and Neuroinflammation in Epilepsy via cGAS/STING Pathway

open access: yesAdvanced Science, EarlyView.
Astrocytic FABP5 promotes mitochondrial stress, cGAS‐STING pathway activation, pyroptosis, and neuroinflammation in epilepsy, contributing to seizure pathology. Genetic targeting of FABP5 or pharmacological inhibition of STING alleviates epileptic phenotypes, highlighting a potential therapeutic strategy for epilepsy.
Chen Chen   +10 more
wiley   +1 more source

The Current situation of Child and adolescent psychological problems and intervention in China

open access: yesAsian Journal of Medical Sciences, 2016
In China, the psychological health problems of children and adolescents have been more and more serious recently. The psychological disorders not only have a lot of adverse effects for children and adolescents, but also were an important source of mental
Wenyan Jiao
doaj   +1 more source

RPLP2 Mediates the Beneficial Effects of Exercise on Stress Resistance Through Muscle–Brain Communication

open access: yesAdvanced Science, EarlyView.
A novel exercise‐inducible myokine acidic ribosomal protein P2 (RPLP2), initially identified from human trials, is presented here, whose circulating levels negatively correlate with clinical anxiety severity. Muscle‐derived RPLP2 enhances hippocampal ribosomal assembly and adult neurogenesis to rescue stress‐induced anxiety deficits.
Peiyu Luo   +18 more
wiley   +1 more source

Analysis of claims of child sexual abuse made with respect to Catholic Church institutions [PDF]

open access: yes, 2017
The Royal Commission has conducted a comprehensive survey of Catholic Church authorities in Australia to gather data about the extent of claims of child sexual abuse made against Catholic Church personnel.
Royal Commission into Institutional Responses to Child Sexual Abuse
core  

Child Sexual Abuse and Exploitation: Guest Editor’s Introduction

open access: yesInternational Journal for Crime, Justice and Social Democracy, 2015
One of the most unnerving aspects of child sexual abuse is that it is constantly manifesting in unexpected ways. The current Royal Commission into Institutional Responses to Child Sexual Abuse has collected testimony of abuse in churches, schools, out-of-
Michael Salter
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

open access: yesAdvanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang   +7 more
wiley   +1 more source

Effects of parenting programs on child abuse prevention: a meta-analytic study [PDF]

open access: yes, 2014
Objectives: Parenting programs are a key component of child and family services to prevent child abuse. By using randomized controlled trials, a number of parenting programs have been proven effective in preventing child abuse.
Chen, M, Chan, EKL
core  

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