Results 81 to 90 of about 2,903,009 (360)

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

open access: yesAdvanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies   +14 more
wiley   +1 more source

Targeted H2S Delivery System Attenuates Blood‐Spinal Cord Barrier Disruption after Spinal Cord Injury by Reshaping the Ferritinophagy Pathway

open access: yesAdvanced Science, EarlyView.
The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen   +11 more
wiley   +1 more source

Knowledge and attitude regarding child abuse among primary health care physician in Abha, Saudi Arabia, 2018

open access: yesJournal of Family Medicine and Primary Care, 2019
Backgrounds: Child abuse or child maltreatment is physical, sexual, or psychological maltreatment or neglect of a child or children, especially by a parent or other caregiver.
Safar A Alsaleem   +8 more
doaj   +1 more source

Children's Human Capabilities and Child Maltreatment

open access: yesJournal de Ciencias Sociales, 2020
There are no known studies that have explored a conceptual basis for valorizing child maltreatment as a human development impediment using the Human Capability Approach.
Clementia Eugene, Tobi L. G. Graafsma
doaj   +1 more source

Updated Trends in Child Maltreatment, 2006. [PDF]

open access: yes, 2008
New data released by the federal government show continuing national declines in sexual and physical abuse in 2006, but no decline in neglect. The data detailed in the attached table and figure, come from the National Child Abuse and Neglect Data System (
Finkelhor, David, Jones, Lisa M.
core   +1 more source

Child Sexual Abuse: Toward a Conceptual Model and Definition

open access: yesTrauma, Violence, & Abuse, 2017
The problem of defining “child sexual abuse” (CSA), and the need to define this concept, has been recognized by major policy bodies and leading researchers since the 1970s.
Benjamin Mathews, D. Collin-Vézina
semanticscholar   +1 more source

Phosphatidic Acid‐TRIM59‐Olig2 Signaling Couples Metabolic Dysfunction to Myelination Failure in PWMI

open access: yesAdvanced Science, EarlyView.
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li   +8 more
wiley   +1 more source

Developing Community Connections: Qualitative Research Regarding Framing Policies [PDF]

open access: yes, 2003
The objective of this phase of research was to determine how Prevent Child Abuse America can effectively frame the organization's communications to advance a broad agenda of policies for children and families, including both policies that directly ...
Meg Bostrom
core  

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

open access: yesAdvanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun   +9 more
wiley   +1 more source

A critical review of child abuse and its management in Africa

open access: yesAfrican Journal of Emergency Medicine, 2017
Introduction: Child abuse in Africa is a major threat to the achievement of the sustainable development goals on the continent and has become increasingly topical with a dramatic increase in recognition and an appreciation of the long term harmful ...
Eben Badoe
doaj   +1 more source

Home - About - Disclaimer - Privacy