Results 71 to 80 of about 2,155,094 (360)
Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization
Advanced Materials, EarlyView.A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab +8 more
wiley +1 more source
Child abuse registration, fetal growth, and preterm birth: a population based study [PDF]
, 2006 Objectives: To study the relation of intra-uterine growth and gestational age with child protection registration in a 20 year whole population birth cohort. Setting: West Sussex area of England.
Bacchus, Claire +4 more
core +1 more source
Advanced Science, EarlyView.Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley +1 more source
Advanced Science, EarlyView.Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong +24 more
wiley +1 more source
The abused and neglected child [PDF]
Jornal de Pediatria, 1994 The study of mistreatment of the child and adolescent, with its historical, social and cultural roots, grow amidst conceptual and methodological difficulties which oppose a more realistic understanding of the problem. The physical and emotional consequences, long-term and immediate, are to a great extent, known.
openaire +2 more sources
The economic burden of child sexual abuse in the United States
International Journal of Child Abuse & Neglect, 2018 The present study provides an estimate of the U.S. economic impact of child sexual abuse (CSA). Costs of CSA were measured from the societal perspective and include health care costs, productivity losses, child welfare costs, violence/crime costs ...
Elizabeth J. Letourneau +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.ANKS1B in the nucleus accumbens plays a critical role in the transition from controlled to escalated cocaine intake. Mechanistically, ANKS1B interacts with CBP to epigenetically suppress FoxO3 through H3K27 acetylation. The ANKS1B‐CBP‐FoxO3 signaling cascade presents a novel theraputic target for the treatment of cocaine addiction.
Liping Yang +15 more
wiley +1 more source
Child Sexual Abuse: Toward a Conceptual Model and Definition
Trauma, Violence, & Abuse, 2017 The problem of defining “child sexual abuse” (CSA), and the need to define this concept, has been recognized by major policy bodies and leading researchers since the 1970s.
Benjamin Mathews, D. Collin-Vézina
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
What you need to know about child sexual abuse [PDF]
This resource introduces some of the key research and statistics on what is known about child sexual abuse: what it is, who harms children, where it takes place, the impact on children and, crucially, what we all can do in ...
Henderson, K, Kewley, S
core +1 more source