FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Analgesia espinal ou epidural?: diferenças entre métodos
Revista Brasileira de Anestesiologia, 2011 FuZhou Wang +5 more
doaj +1 more source
The effect of the elderly and child care on household carbon emissions. [PDF]
Heliyon, 2023 Sun Q, Lu G.
europepmc +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Socio-Emotional Outcomes of Child Care Participation: Results of a Four-Year Longitudinal Cohort Study. [PDF]
Children (Basel)Kingsbury M, Findlay L.
europepmc +1 more source
The development and validation of the CARe Burn Scale: Child Form: a parent-proxy-reported outcome measure assessing quality of life for children aged 8 years and under living with a burn injury [PDF]
, 2020 Catrin Griffiths +6 more
openalex +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Young Children's Dietary Quality in Family Child Care and in Their Own Home. [PDF]
J Acad Nutr Diet, 2023 Zaltz DA +5 more
europepmc +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
Children's outdoor play at early learning and child care centres: Examining the impact of environmental play features on children's play behaviour. [PDF]
PLoS OneRamsden R, Pike I, Thorne S, Brussoni M.
europepmc +1 more source