Results 91 to 100 of about 3,390,395 (296)

The Interactive Child Distress Screener: development and preliminary feasibility testing [PDF]

open access: yes, 2018
Background Early identification of child emotional and behavioral concerns is essential for the prevention of mental health problems; however, few suitable child-reported screening measures are available.
Day, Jamin   +3 more
core   +3 more sources

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

Strategies of Interaction between Parents and Preschool Children and Features of Ideas about Parenting

open access: yesПсихолого-педагогические исследования
This article reveals the problem of the relationship between the strategies of interaction of parents with preschool children and ideas about parenting in the context of studying the phenomenon of conscious parenting. Conscious and responsible
T.P. Avdulova   +2 more
doaj   +1 more source

Ending Child Marriage in a Generation: What Research is Needed? [PDF]

open access: yes, 2014
In recent years, the obstacles that child marriage poses to development and to the achievement of the Millennium Development Goals have been widely recognized. Varied responses to the problem have been devised.
Margaret E. Greene
core  

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Intrapericardial immature teratoma with pericardial effusion in a 4-month-old boy

open access: yesJournal of Pediatric Surgery Case Reports, 2020
Intrapericardial teratoma is an extremely rare mediastinal teratoma that arises at the junction of the ascending aorta and right atrial appendage. The teratoma is often complicated by massive pericardial effusion that compresses the heart and lungs ...
Teizaburo Mori   +14 more
doaj  

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