Results 101 to 110 of about 1,264,995 (315)

Interactive technology use and child development: A systematic review

open access: yes, 2023
BackgroundThere is mixed evidence regarding the impact of interactive digital devices on child development. Tentatively some studies suggested that the use of digital devices may correlate negatively with language, executive function, and motor skills ...
Robinson, Sue,   +16 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Chemicals, nutrition, and autism spectrum disorder: a mini-review

open access: yesFrontiers in Neuroscience, 2016
The rapid increase of the prevalence of autism spectrum disorder (ASD) suggests that exposure to chemicals may impact the development of ASD. Therefore, we reviewed literature on the following chemicals, nutrient to investigate their association with ASD:
Takeo eFujiwara   +5 more
doaj   +1 more source

Group Photo at the Duquesne University Child Development Center

open access: yes, 2020
WIS is pleased to sponsor several visits from the Carnegie Science Center to the children at the Duquesne University Child Development Center.
Child Development Center, Duquesne University
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Autism spectrum: parents’ perspectives reflecting the different needs of different families

open access: yesBMC Pediatrics
Background Parents of children on the autism spectrum often face great challenges in the care of their child. Early support tailored to families’ individual needs is therefore crucial for the development and quality of life of both children on the autism
Nadja K. Battanta   +3 more
doaj   +1 more source

Anthropometric Failures: Nutrition, Early Child Interventions and Emotional, and Cognitive Development Potentials

open access: yes, 2007
This presentation deals with the following issue: how poverty, poor health, nutrition and care affect child development. The author reviews a series of "capabilities approaches," including concepts such as the conversion of primary good into the person ...
Inter-American Development Bank
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Understanding child neglect [PDF]

open access: yes, 2014
Child neglect is one of the most common forms of maltreatment. Neglect is a topic that encompasses complex issues, many of which are also emerging research areas. This paper aims to provide a broad overview of these issues in relation to current thinking
Debbie Scott
core  

Goal setting with mothers in child development services

open access: yes, 2014
Aim The aim of this grounded theory study was to explore mothers' perspectives of the processes of collaborative goal setting in multidisciplinary child development services involving follow-up home therapy.
Harvey, A.   +4 more
core   +1 more source

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