Results 101 to 110 of about 19,059,317 (408)

Autism spectrum: parents’ perspectives reflecting the different needs of different families

open access: yesBMC Pediatrics
Background Parents of children on the autism spectrum often face great challenges in the care of their child. Early support tailored to families’ individual needs is therefore crucial for the development and quality of life of both children on the autism
Nadja K. Battanta   +3 more
doaj   +1 more source

Association between early child development trajectories and adult cognitive function in a 50-year longitudinal study in Guatemala [PDF]

open access: gold, 2021
Inés González-Casanova   +6 more
openalex   +1 more source

TREX1, a predator for treating MSI‐H tumors?

open access: yesMolecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya   +2 more
wiley   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

open access: yesFEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu   +6 more
wiley   +1 more source

Child Care Feeding Programs Support Young Children's Healthy Development [PDF]

open access: yes, 2010
New research by Children's HealthWatch shows that toddlers from low-income families who receive meals from their child care provider - those likely to be receiving CACFP - are in better health, have decreased risk for hospitalization, and are at ...
Annie Gayman   +5 more
core  

“… so what?” Attitudes of the voluntary sector towards child protection in sports clubs [PDF]

open access: yes, 2002
There is both growing concern about ethical standards in sport and also rapid expansion in the number of local and national schemes designed to encourage youth sports development.
Brackenridge, CH
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Maternal adverse childhood experiences on child growth and development in rural Pakistan: An observational cohort study

open access: gold, 2023
Esther O. Chung   +8 more
openalex   +2 more sources

Household Choices and Child Development [PDF]

open access: yes
The growth in labor market participation among women with young children has raised concerns about the potential negative impact of the mother's absence from home on child outcomes.
Christopher Flinn   +2 more
core  

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

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