Results 121 to 130 of about 18,495,960 (408)

Altered white matter connectivity of ventral language networks in autism spectrum disorder: An automated fiber quantification analysis with multi-site datasets

open access: yesNeuroImage
Comprehension and pragmatic deficits are prevalent in autism spectrum disorder (ASD) and are potentially linked to altered connectivity in the ventral language networks.
Min Li   +9 more
doaj  

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

CECP GSO Research Exchange Conference 2011 [PDF]

open access: yes, 2011
The following literature review discusses potential non-medical benefits that may result from child and adolescent interaction with animals, and the practitioner or educator preferences regarding animal species used in Applied Animal Therapy.
Johnson, Kathryn
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Income and Child Development [PDF]

open access: yes
We examine how income influences pre-school children’s cognitive and behavioral development, using new data from a birth cohort study of children born at the end of the 20th century.
Christina Paxson   +2 more
core  

Effects of parenting style upon psychological well-being of young adults: Exploring the relations among parental care, locus of control, and depression. [PDF]

open access: yes, 1997
The current study explores the relations among parenting styles and depression among a representative longitudinal sample of 642 young Dutch adults. We assumed that if parents show their involvement during the first sixteen years of the lives of their ...
Dohrenwend B.P.   +12 more
core   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

Measuring Within and Between Group Inequality in Early-Life Mortality Over Time: A Bayesian Approach with Application to India [PDF]

open access: yesarXiv, 2018
Most studies on inequality in infant and child mortality compare average mortality rates between large groups of births, for example, comparing births from different countries, income groups, ethnicities, or different times. These studies do not measure within-group disparities.
arxiv  

Maternal depression and children's adjustment problems : the role of mothers' affective reactivity [PDF]

open access: yes, 2015
textMothers with depressive symptoms often express more negative emotions than other mothers, react more punitively, and express more frustration (e.g., Belsky, 1984).
Moed, Anat
core   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

open access: yesFEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal   +3 more
wiley   +1 more source

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