Results 161 to 170 of about 966,714 (352)

NFS1 Regulates IDH2 to Attenuate Abdominal Aortic Aneurysms via Interacting With SP2

open access: yesAdvanced Science, EarlyView.
The loss of NFS1 leads to its reduced binding with the transcription factor SP2, resulting in decreased expression of the downstream gene Idh2. This causes a shift in energy supply toward glycolysis in VSMCs, ultimately contributing to the occurrence and progression of AAA.
Luzheng Zhang   +9 more
wiley   +1 more source

Lowering Child Mortality in Poor Countries: The Power of Knowledgeable Parents [PDF]

open access: yes
Why do over 20% of children die in some poor countries, while in others only 2% die? We examine this question using survey data covering 278,000 children in 45 low-income countries.
Peter Boone, Zhaoguo Zhan
core  

Expandable Nanocomposite Shape‐Memory Hemostat for the Treatment of Noncompressible Hemorrhage

open access: yesAdvanced Science, EarlyView.
A nanocomposite‐coated shape memory foam rapidly expands, accelerates clotting, and reduces blood loss in vivo. Its fast volumetric expansion and strong procoagulant activity make it a promising hemostat for treating deep, noncompressible hemorrhage.
Saptarshi Biswas   +12 more
wiley   +1 more source

Does the Mortality Decline Promote Economic Growth? [PDF]

open access: yes
This paper analyzes qualitatively and quantitatively the e ects of declining mortality rates on fertility, education and economic growth. The analysis demonstrates that if individuals are prudent in the face of uncertainty about child survival, a decline
Sebnem Kalemli-Ozcan
core  

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

open access: yesAdvanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu   +13 more
wiley   +1 more source

Prevalence of sepsis, malaria, malnutrition, and pneumonia in the causal chain of death among minimally invasive tissue sampling (MITS)-eligible decedents aged 28 days to 59 months enrolled in the Kenya Child Health and Mortality Prevention Surveillance (CHAMPS) sites from February 1, 2018, to March 31, 2022.

open access: green
Susan Gachau (5233919)   +15 more
openalex   +1 more source

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